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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000083273
Molecular formula	C23H30N6O4
IUPAC name	9-(3-methoxyphenyl)-1,7-dimethyl-3-(2-morpholin-4-ylethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Molecular weight	454.531
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	1.7
Synonyms	CHEMBL1543154 ST51077086 9-(3-methoxyphenyl)-1,7-dimethyl-3-[2-(4-morpholinyl)ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione MCULE-2256929506 AC1LDGZ3 MolPort-002-643-536 9-(3-methoxyphenyl)-1,7-dimethyl-3-(2-morpholin-4-ylethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione BDBM67151 cid_666914 STK581265 9-(3-methoxyphenyl)-1,7-dimethyl-3-[2-(morpholin-4-yl)ethyl]-1H,2H,3H,4H,6H,7H,8H,9H-pyrimido[1,2-g]purine-2,4-dione 848206-61-1 AKOS001299554 SMR000048212 9-(3-methoxyphenyl)-1,7-dimethyl-3-(2-morpholinoethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-quinone HMS2412A21 Z223843850 9-(3-methoxyphenyl)-1,7-dimethyl-3-[2-(morpholin-4-yl)ethyl]-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione MLS002584193 9-(3-methoxyphenyl)-1,7-dimethyl-3-(2-morpholin-4-ylethyl)-1,3,5-trihydro-6H,7 H,8H-1,3-diazaperhydroino[1,2-h]purine-2,4-dione AKOS016337474 [ Show all ]
Inchi Key	CVSSLUCDGJDGHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H30N6O4/c1-16-14-28(17-5-4-6-18(13-17)32-3)22-24-20-19(29(22)15-16)21(30)27(23(31)25(20)2)8-7-26-9-11-33-12-10-26/h4-6,13,16H,7-12,14-15H2,1-3H3
PubChem CID	666914
ChEMBL	CHEMBL1543154
IUPHAR	N/A
BindingDB	67151
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51756	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
51755	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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