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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000770828
Molecular formula	C15H17ClN4O2S2
IUPAC name	N-(2-chloro-5-nitrophenyl)-2-(diethylamino)-4-methyl-1,3-thiazole-5-carbothioamide
Molecular weight	384.897
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.8
Synonyms	HMS2705P15 SMR000344072 AKOS034448581 MolPort-005-861-239 CHEMBL1511616 N-(2-chloro-5-nitrophenyl)-2-(diethylamino)-4-methyl-1,3-thiazole-5-carbothioamide 745026-70-4 MCULE-4277380445 Z55920525 BDBM67287 N-(2-chloranyl-5-nitro-phenyl)-2-(diethylamino)-4-methyl-1,3-thiazole-5-carbothioamide cid_2100716 N-(2-chloro-5-nitrophenyl)-2-(diethylamino)-4-methyl-5-thiazolecarbothioamide AC1M1L8Z ZINC13636267 N-(2-chloro-5-nitro-phenyl)-2-(diethylamino)-4-methyl-thiazole-5-carbothioamide [ Show all ]
Inchi Key	DKCVZWQRTVXRGB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17ClN4O2S2/c1-4-19(5-2)15-17-9(3)13(24-15)14(23)18-12-8-10(20(21)22)6-7-11(12)16/h6-8H,4-5H2,1-3H3,(H,18,23)
PubChem CID	2100716
ChEMBL	CHEMBL1511616
IUPHAR	N/A
BindingDB	67287
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62095	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
62094	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
62096	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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