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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000584397
Molecular formula	C19H20N2OS2
IUPAC name	(5E)-3-prop-2-enyl-2-sulfanylidene-5-[(2E)-2-(1,3,3-trimethylindol-2-ylidene)ethylidene]-1,3-thiazolidin-4-one
Molecular weight	356.502
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.0
Synonyms	(5E)-3-allyl-2-thioxo-5-[(2E)-2-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)ethylidene]-1,3-thiazolidin-4-one CHEMBL1369513 (5E)-3-prop-2-enyl-2-sulfanylidene-5-[(2E)-2-(1,3,3-trimethylindol-2-ylidene)ethylidene]-1,3-thiazolidin-4-one BDBM51017 ZINC5128028 (5E)-3-allyl-2-thioxo-5-[(2E)-2-(1,3,3-trimethylindolin-2-ylidene)ethylidene]thiazolidin-4-one cid_12005182 MolPort-003-896-494 (5E)-3-prop-2-enyl-2-sulfanylidene-5-[(2E)-2-(1,3,3-trimethyl-2-indolylidene)ethylidene]-4-thiazolidinone HMS2597J24 AKOS001486167 SMR000203560 [ Show all ]
Inchi Key	BNRSQCUOPLBUHF-RWPWKDLBSA-N
Inchi ID	InChI=1S/C19H20N2OS2/c1-5-12-21-17(22)15(24-18(21)23)10-11-16-19(2,3)13-8-6-7-9-14(13)20(16)4/h5-11H,1,12H2,2-4H3/b15-10+,16-11+
PubChem CID	12005182
ChEMBL	CHEMBL1369513
IUPHAR	N/A
BindingDB	51017
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
28382	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
28381	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319
28383	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
28384	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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