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Name | Lysergide |
---|---|
Molecular formula | C20H25N3O |
IUPAC name | (6aR,9R)-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
Molecular weight | 323.44 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 1 |
XlogP | 3.0 |
Synonyms | (8alpha)-N,N-Diethyl-6-Methyl-9,10-Didehydroergoline-8-Carboxamide 752-EP2308839A1 6482-EP1441224A2 752-EP2308871A1 752-EP2270006A1 [ Show all ] |
Inchi Key | VAYOSLLFUXYJDT-RDTXWAMCSA-N |
Inchi ID | InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1 |
PubChem CID | 5761 |
ChEMBL | CHEMBL263881 |
IUPHAR | 17 |
BindingDB | 21342, 50241702 |
DrugBank | DB04829 |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
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GLASS ID | Name | UniProt | Gene | Species | Length |
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350526 | 5-hydroxytryptamine receptor 1A | P08908 | HTR1A | Homo sapiens (Human) | 422 |
350541 | 5-hydroxytryptamine receptor 1A | P19327 | Htr1a | Rattus norvegicus (Rat) | 422 |
350544 | 5-hydroxytryptamine receptor 1D | P28221 | HTR1D | Homo sapiens (Human) | 377 |
350549 | 5-hydroxytryptamine receptor 1D | P11614 | HTR1D | Canis lupus familiaris (Dog) | 377 |
350548 | 5-hydroxytryptamine receptor 1E | P28566 | HTR1E | Homo sapiens (Human) | 365 |
350529 | 5-hydroxytryptamine receptor 2A | P14842 | Htr2a | Rattus norvegicus (Rat) | 471 |
350533 | 5-hydroxytryptamine receptor 2A | P28223 | HTR2A | Homo sapiens (Human) | 471 |
350538 | 5-hydroxytryptamine receptor 2B | P41595 | HTR2B | Homo sapiens (Human) | 481 |
555036 | 5-hydroxytryptamine receptor 2B | P30994 | Htr2b | Rattus norvegicus (Rat) | 479 |
350528 | 5-hydroxytryptamine receptor 2C | P28335 | HTR2C | Homo sapiens (Human) | 458 |
350536 | 5-hydroxytryptamine receptor 2C | P08909 | Htr2c | Rattus norvegicus (Rat) | 460 |
556912 | 5-hydroxytryptamine receptor 4 | Q62758 | Htr4 | Rattus norvegicus (Rat) | 406 |
350534 | 5-hydroxytryptamine receptor 5A | P47898 | HTR5A | Homo sapiens (Human) | 357 |
350543 | 5-hydroxytryptamine receptor 5B | P35365 | Htr5b | Rattus norvegicus (Rat) | 370 |
350525 | 5-hydroxytryptamine receptor 6 | P50406 | HTR6 | Homo sapiens (Human) | 440 |
350537 | 5-hydroxytryptamine receptor 6 | P31388 | Htr6 | Rattus norvegicus (Rat) | 436 |
350524 | 5-hydroxytryptamine receptor 7 | P34969 | HTR7 | Homo sapiens (Human) | 479 |
350539 | 5-hydroxytryptamine receptor 7 | P32305 | Htr7 | Rattus norvegicus (Rat) | 448 |
556911 | 5-hydroxytryptamine receptor 7 | P50407 | HTR7 | Cavia porcellus (Guinea pig) | 446 |
556913 | Alpha-1A adrenergic receptor | P43140 | Adra1a | Rattus norvegicus (Rat) | 466 |
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