You can:
| Name | Endothelin-1 receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Ednra |
| Synonym | endothelin A receptor Endothelin receptor type A {ECO:0000312|RGD:2535} ENDOR endothelin-1 receptor ET-A [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 426 |
| Amino acid sequence | MGVLCFLASFWLALVGGAIADNAERYSANLSSHVEDFTPFPGTEFNFLGTTLQPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEQHRTCMLNATTKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNHNTERSSHKDSMN |
| UniProt | P26684 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4566 |
| IUPHAR | 219 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 481 |  BDBM50279801 | C106H153N25O32S5 | 2449.83 | 40 / 32 | -5.0 | No |
| 842 |  CHEMBL96847 | C26H29N3O6S | 511.593 | 7 / 1 | 4.1 | No |
| 1074 |  CHEMBL321831 | C28H42N2O6 | 502.652 | 7 / 1 | 2.1 | No |
| 1506 |  CHEMBL326861 | C27H36N2O7S | 532.652 | 9 / 1 | 1.4 | No |
| 1746 |  CHEMBL94918 | C24H25N3O6S | 483.539 | 7 / 1 | 3.3 | Yes |
| 2362 |  CHEMBL109736 | C26H32N2O5 | 452.551 | 6 / 1 | 1.0 | Yes |
| 2910 |  CHEMBL287819 | C33H30N6OS | 558.704 | 7 / 0 | 7.3 | No |
| 3361 |  CHEMBL367444 | C29H33N5O7S3 | 659.791 | 13 / 2 | 4.9 | No |
| 3375 |  CHEMBL9139 | C27H34N2O6 | 482.577 | 7 / 1 | 1.7 | Yes |
| 4112 |  CHEMBL326191 | C30H40N2O5 | 508.659 | 6 / 1 | 2.6 | No |
| 4182 |  CHEMBL55853 | C25H19NO6 | 429.428 | 6 / 1 | 4.3 | Yes |
| 4571 |  CHEMBL9082 | C25H29NO6 | 439.508 | 7 / 1 | 1.5 | Yes |
| 5089 |  CHEMBL328786 | C20H15NO5S | 381.402 | 6 / 1 | 4.5 | Yes |
| 5468 |  CHEMBL348685 | C20H22N2O3S2 | 402.527 | 6 / 1 | 4.6 | Yes |
| 5477 |  CHEMBL177378 | C31H32O9 | 548.588 | 9 / 1 | 5.7 | No |
| 5481 |  CHEMBL92607 | C22H18O3 | 330.383 | 3 / 1 | 5.0 | Yes |
| 5962 |  CHEMBL315280 | C27H21ClN2O7 | 520.922 | 8 / 2 | 5.3 | No |
| 6576 |  CHEMBL9141 | C24H28N2O6 | 440.496 | 7 / 2 | 0.6 | Yes |
| 6864 |  CHEMBL368255 | C30H41N5O5 | 551.688 | 6 / 4 | 5.0 | No |
| 6926 |  CHEMBL174235 | C24H18N2O5 | 414.417 | 7 / 1 | 4.6 | Yes |
| 7555 |  CHEMBL56349 | C26H21NO6 | 443.455 | 6 / 1 | 3.4 | Yes |
| 7893 |  CHEMBL38270 | C28H21K2NO7 | 561.673 | 8 / 0 | N/A | No |
| 8654 |  CHEMBL151525 | C23H26N2O5S | 442.53 | 7 / 1 | 5.6 | No |
| 8861 |  CHEMBL129220 | C30H40N2O7 | 540.657 | 8 / 1 | 2.4 | No |
| 8908 |  CHEMBL112770 | C29H46N2O5 | 502.696 | 6 / 1 | 4.1 | No |
| 9303 |  CHEMBL176992 | C30H41N5O4S | 567.749 | 6 / 4 | 5.6 | No |
| 9696 |  CHEMBL93411 | C20H16ClNO4S | 401.861 | 5 / 1 | 5.2 | No |
| 10755 |  CHEMBL109474 | C29H44N2O6 | 516.679 | 7 / 1 | 2.3 | No |
| 11198 |  CHEMBL266337 | C25H30N2O6 | 454.523 | 7 / 2 | 1.0 | Yes |
| 11376 |  CHEMBL266143 | C26H26N2O5 | 446.503 | 7 / 1 | 1.3 | Yes |
| 11840 |  CHEMBL146845 | C24H31N3O3S | 441.59 | 6 / 2 | 6.1 | No |
| 11955 |  CHEMBL368270 | C29H22O6 | 466.489 | 6 / 1 | 6.0 | No |
| 12149 |  CHEMBL27344 | C18H21N3O3S | 359.444 | 6 / 1 | 3.8 | Yes |
| 12264 |  CHEMBL293702 | C22H22O6 | 382.412 | 6 / 1 | 4.5 | Yes |
| 12359 |  CHEMBL94141 | C23H21NO4S | 407.484 | 6 / 1 | 4.5 | Yes |
| 12361 |  CHEMBL94071 | C23H21NO4S | 407.484 | 6 / 1 | 4.5 | Yes |
| 12364 |  CHEMBL90320 | C23H21NO4S | 407.484 | 6 / 1 | 4.5 | Yes |
| 12377 |  CHEMBL65292 | C27H32O7 | 468.546 | 7 / 1 | 6.3 | No |
| 12876 |  CHEMBL286682 | C14H19N3O3S | 309.384 | 6 / 2 | 2.6 | Yes |
| 13534 |  CHEMBL176093 | C29H39N5O5 | 537.661 | 6 / 4 | 3.8 | No |
| 13538 |  CHEMBL172030 | C31H32N6O7S3 | 696.812 | 14 / 2 | 5.2 | No |
| 13611 |  CHEMBL172543 | C33H40N6O5 | 600.72 | 7 / 3 | 4.3 | No |
| 13858 |  4-amino-n-(1,3,4-thiadiazol-2-yl)benzenesulfonamide | C8H8N4O2S2 | 256.298 | 7 / 2 | 0.5 | Yes |
| 14301 |  CHEMBL299328 | C27H21N2O8S- | 533.531 | 11 / 0 | 5.2 | No |
| 14994 |  CHEMBL172506 | C34H42N6O5 | 614.747 | 7 / 3 | 4.6 | No |
| 15003 |  CHEMBL173054 | C25H23NO4 | 401.462 | 5 / 1 | 5.5 | No |
| 16548 |  CHEMBL30075 | C15H15N3O3S | 317.363 | 6 / 2 | 2.3 | Yes |
| 16642 |  CID 44270771 | C108H161N25O32S5 | 2481.92 | 40 / 36 | -5.5 | No |
| 17025 |  CHEMBL174229 | C20H15NO4S | 365.403 | 6 / 1 | 4.0 | Yes |
| 17660 |  CHEMBL1627022 | C27H27BrN5NaO5S | 636.497 | 10 / 1 | N/A | No |
| 18445 |  CHEMBL367208 | C29H34N6O4 | 530.629 | 5 / 5 | 4.0 | No |
| 18735 |  CHEMBL149050 | C20H22N2O5S2 | 434.525 | 7 / 1 | 3.4 | Yes |
| 18966 |  CHEMBL426413 | C30H40N6O4 | 548.688 | 5 / 5 | 4.2 | No |
| 19175 |  CHEMBL61211 | C27H24O7 | 460.482 | 7 / 1 | 4.9 | Yes |
| 19176 |  CHEMBL264543 | C27H24O7 | 460.482 | 7 / 1 | 4.9 | Yes |
| 19178 |  CHEMBL62395 | C27H24O7 | 460.482 | 7 / 1 | 4.9 | Yes |
| 19649 |  CHEMBL434082 | C21H24N2O3S | 384.494 | 5 / 1 | 5.2 | No |
| 19764 |  CHEMBL157742 | C27H21NO6 | 455.466 | 6 / 1 | 4.9 | Yes |
| 20390 |  CHEMBL110904 | C28H42N2O5 | 486.653 | 6 / 1 | 3.3 | Yes |
| 20439 |  CHEMBL172297 | C31H36N4O7S3 | 672.83 | 12 / 2 | 6.1 | No |
| 21611 |  CHEMBL25854 | C16H17N3O3S | 331.39 | 6 / 1 | 3.0 | Yes |
| 23496 |  BDBM50284278 | C109H159N27O32S5 | 2519.93 | 41 / 37 | -6.7 | No |
| 24152 |  CHEMBL113379 | C26H32N2O5 | 452.551 | 6 / 1 | 1.0 | Yes |
| 442642 |  CHEMBL3400988 | C26H24O7 | 448.471 | 7 / 1 | 4.2 | Yes |
| 25209 |  CHEMBL156269 | C27H21NO6 | 455.466 | 6 / 1 | 4.9 | Yes |
| 25285 |  CHEMBL88011 | C24H23ClN2O6S | 502.966 | 8 / 2 | 4.9 | No |
| 25490 |  CHEMBL8925 | C28H36N2O6 | 496.604 | 6 / 1 | 4.6 | Yes |
| 25616 |  CHEMBL343867 | C20H23N3O3S | 385.482 | 6 / 2 | 4.1 | Yes |
| 25969 |  CHEMBL175545 | C26H24O6 | 432.472 | 6 / 1 | 4.9 | Yes |
| 27638 |  CHEMBL419367 | C28H34F4N2O7S | 618.641 | 13 / 1 | 2.5 | No |
| 28647 |  CHEMBL8677 | C27H27NO6 | 461.514 | 7 / 1 | 2.0 | Yes |
| 28768 |  CHEMBL114074 | C29H41N3O6 | 527.662 | 8 / 1 | 2.5 | No |
| 30618 |  CHEMBL359152 | C22H26N2O4S | 414.52 | 6 / 1 | 4.9 | Yes |
| 30926 |  CHEMBL323789 | C28H38N2O7S | 546.679 | 9 / 1 | 1.9 | No |
| 30945 |  CHEMBL92965 | C27H25NO4S | 459.56 | 6 / 1 | 5.4 | No |
| 442881 |  CHEMBL3400997 | C24H19N3O4S | 445.493 | 8 / 1 | 4.3 | Yes |
| 31246 |  CHEMBL173431 | C22H18N2O4 | 374.396 | 6 / 1 | 3.7 | Yes |
| 31313 |  CHEMBL322799 | C28H39N3O7 | 529.634 | 8 / 1 | 0.2 | No |
| 31731 |  CHEMBL91753 | C25H24N2O4S | 448.537 | 6 / 2 | 4.7 | Yes |
| 31791 |  CHEMBL9334 | C28H36N2O6 | 496.604 | 7 / 1 | 2.0 | Yes |
| 32262 |  CHEMBL174573 | C29H28O10 | 536.533 | 10 / 1 | 4.6 | No |
| 32517 |  CHEMBL418667 | C21H20O6 | 368.385 | 6 / 1 | 3.9 | Yes |
| 32949 |  CHEMBL155708 | C29H26N2O8S | 562.593 | 9 / 1 | 4.0 | No |
| 33580 |  CHEMBL149060 | C20H22N2O3S | 370.467 | 5 / 1 | 4.8 | Yes |
| 33905 |  CHEMBL331577 | C25H32N2O5 | 440.54 | 6 / 1 | 0.9 | Yes |
| 34513 |  CHEMBL96644 | C25H25N3O6S | 495.55 | 7 / 1 | 3.2 | Yes |
| 34702 |  CHEMBL368461 | C29H32FN5O5 | 549.603 | 7 / 4 | 4.4 | No |
| 34725 |  CHEMBL105490 | C21H24N2O3S | 384.494 | 5 / 1 | 4.9 | Yes |
| 34787 |  CHEMBL366544 | C30H42N6O4 | 550.704 | 5 / 5 | 4.7 | No |
| 35194 |  CHEMBL368558 | C30H40N2O6 | 524.658 | 7 / 1 | 2.6 | No |
| 37074 |  CHEMBL26079 | C19H19N3O4S | 385.438 | 6 / 1 | 2.7 | Yes |
| 37312 |  CHEMBL304460 | C18H18ClN3O6S3 | 503.987 | 9 / 2 | 3.6 | No |
| 37579 |  CHEMBL300066 | C24H27N3O4S2 | 485.617 | 8 / 1 | 5.3 | No |
| 37589 |  CHEMBL174818 | C31H41N5O7 | 595.697 | 8 / 4 | 4.2 | No |
| 39062 |  CHEMBL177221 | C26H22O7 | 446.455 | 7 / 1 | 4.7 | Yes |
| 39092 |  CHEMBL29705 | C17H19N3O3S | 345.417 | 6 / 1 | 3.1 | Yes |
| 40175 |  CHEMBL148853 | C22H26N2O4S | 414.52 | 6 / 1 | 5.2 | No |
| 40428 |  CHEMBL368853 | C29H32FN5O5 | 549.603 | 7 / 4 | 4.4 | No |
| 40805 |  CHEMBL417050 | C24H18O6 | 402.402 | 6 / 1 | 4.2 | Yes |
| 42201 |  CHEMBL315752 | C24H25ClN2O4 | 440.924 | 5 / 1 | 6.1 | No |
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