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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL149050
Molecular formula	C20H22N2O5S2
IUPAC name	N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-(4-propan-2-ylsulfonylphenyl)benzenesulfonamide
Molecular weight	434.525
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.4
Synonyms	BDBM50068733 4''-(Propane-2-sulfonyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Inchi Key	BACQXHYPRKBLQD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22N2O5S2/c1-13(2)28(23,24)17-11-9-16(10-12-17)18-7-5-6-8-19(18)29(25,26)22-20-14(3)15(4)21-27-20/h5-13,22H,1-4H3
PubChem CID	10598958
ChEMBL	CHEMBL149050
IUPHAR	N/A
BindingDB	50068733
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18734	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
18735	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426
18736	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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