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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL367444
Molecular formula	C29H33N5O7S3
IUPAC name	N-[2-cyclopropyl-5-(2-methoxyphenoxy)-6-[3-(thiophen-2-ylsulfonylamino)propoxy]pyrimidin-4-yl]-5-propan-2-ylpyridine-2-sulfonamide
Molecular weight	659.791
Hydrogen bond acceptor	13
Hydrogen bond donor	2
XlogP	4.9
Synonyms	N-[3-[2-Cyclopropyl-5-(2-methoxyphenoxy)6-(5-isopropyl-2-pyridinylsulfonylamino)-4-pyrimidinyloxy]propyl]thiophene-2-sulfonamide 5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(thiophene-2-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide SCHEMBL7194048 BDBM50124446
Inchi Key	AEDJOIBTFWFFLB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H33N5O7S3/c1-19(2)21-13-14-24(30-18-21)43(35,36)34-28-26(41-23-9-5-4-8-22(23)39-3)29(33-27(32-28)20-11-12-20)40-16-7-15-31-44(37,38)25-10-6-17-42-25/h4-6,8-10,13-14,17-20,31H,7,11-12,15-16H2,1-3H3,(H,32,33,34)
PubChem CID	9917706
ChEMBL	CHEMBL367444
IUPHAR	N/A
BindingDB	50124446
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3363	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
3364	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
3361	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426
3362	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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