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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL157742
Molecular formula	C27H21NO6
IUPAC name	4-(4-methoxyphenyl)-1-[(2-methoxyphenyl)methyl]-2-oxo-[1]benzofuro[3,2-b]pyridine-3-carboxylic acid
Molecular weight	455.466
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	1-(2-Methoxybenzyl)-2-oxo-4-(4-methoxyphenyl)-1,2-dihydrobenzofuro[3,2-b]pyridine-3-carboxylic acid 1-(2-Methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid BDBM50075417 SCHEMBL6314933
Inchi Key	BBQVZZLPYFHCQZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H21NO6/c1-32-18-13-11-16(12-14-18)22-23(27(30)31)26(29)28(15-17-7-3-5-9-20(17)33-2)24-19-8-4-6-10-21(19)34-25(22)24/h3-14H,15H2,1-2H3,(H,30,31)
PubChem CID	10173807
ChEMBL	CHEMBL157742
IUPHAR	N/A
BindingDB	50075417
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19765	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
19764	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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