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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL174229
Molecular formula	C20H15NO4S
IUPAC name	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-phenylacetic acid
Molecular weight	365.403
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.0
Synonyms	[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-phenyl-acetic acid (RS)-[2-Cyano-5-(3-thienylmethoxy)phenoxy]-phenylacetic Acid AXRWHVQKSIEFTF-UHFFFAOYSA-N (RS)-[2-Cyano-5-(3-thienylmethoxy)phenoxy]phenylacetic acid BDBM50085852 SCHEMBL8119563 [ Show all ]
Inchi Key	AXRWHVQKSIEFTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H15NO4S/c21-11-16-6-7-17(24-12-14-8-9-26-13-14)10-18(16)25-19(20(22)23)15-4-2-1-3-5-15/h1-10,13,19H,12H2,(H,22,23)
PubChem CID	9863916
ChEMBL	CHEMBL174229
IUPHAR	N/A
BindingDB	50085852
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17024	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
17025	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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