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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL148853
Molecular formula	C22H26N2O4S
IUPAC name	N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-[2-methoxy-4-(2-methylpropyl)phenyl]benzenesulfonamide
Molecular weight	414.52
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.2
Synonyms	N-(3,4-Dimethylisoxazole-5-yl)-2'-methoxy-4'-(2-methylpropyl)-1,1'-biphenyl-2-sulfonamide 4''-Isobutyl-2''-methoxy-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide SCHEMBL6772995 BDBM50068743
Inchi Key	CEQZTVDVWMGLDZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N2O4S/c1-14(2)12-17-10-11-18(20(13-17)27-5)19-8-6-7-9-21(19)29(25,26)24-22-15(3)16(4)23-28-22/h6-11,13-14,24H,12H2,1-5H3
PubChem CID	10597897
ChEMBL	CHEMBL148853
IUPHAR	N/A
BindingDB	50068743
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
40176	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
40174	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
40175	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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