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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL434082
Molecular formula	C21H24N2O3S
IUPAC name	N-(4,5-dimethyl-1,2-oxazol-3-yl)-2-[4-(2-methylpropyl)phenyl]benzenesulfonamide
Molecular weight	384.494
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50068685 N-(4,5-Dimethylisoxazole-3-yl)-4'-(2-methylpropyl)-1,1'-biphenyl-2-sulfonamide 4''-Isobutyl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide SCHEMBL6767700
Inchi Key	BBNRKSPDJHJZHA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24N2O3S/c1-14(2)13-17-9-11-18(12-10-17)19-7-5-6-8-20(19)27(24,25)23-21-15(3)16(4)26-22-21/h5-12,14H,13H2,1-4H3,(H,22,23)
PubChem CID	10762600
ChEMBL	CHEMBL434082
IUPHAR	N/A
BindingDB	50068685
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19650	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
19649	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426
19651	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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