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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL105490
Molecular formula	C21H24N2O3S
IUPAC name	N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-[4-(2-methylpropyl)phenyl]benzenesulfonamide
Molecular weight	384.494
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.9
Synonyms	4''-Isobutyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide BDBM50068742 SCHEMBL6778007 4'-Isobutyl-N-(3,4-dimethyl-5-isoxazolyl)biphenyl-2-sulfonamide
Inchi Key	BWTQPWDURQZRKQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24N2O3S/c1-14(2)13-17-9-11-18(12-10-17)19-7-5-6-8-20(19)27(24,25)23-21-15(3)16(4)22-26-21/h5-12,14,23H,13H2,1-4H3
PubChem CID	10691437
ChEMBL	CHEMBL105490
IUPHAR	N/A
BindingDB	50068742
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34722	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
34724	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
34723	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
34725	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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