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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL304460
Molecular formula	C18H18ClN3O6S3
IUPAC name	3-[(4-chloro-3-methyl-1,2-oxazol-5-yl)sulfamoyl]-N-(2,4-dimethyl-6-methylsulfonylphenyl)thiophene-2-carboxamide
Molecular weight	503.987
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	3.6
Synonyms	BDBM50143797 SCHEMBL5212196 3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-methanesulfonyl-4,6-dimethyl-phenyl)-amide
Inchi Key	CAMTYBNKRSCYOA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H18ClN3O6S3/c1-9-7-10(2)15(13(8-9)30(4,24)25)20-17(23)16-12(5-6-29-16)31(26,27)22-18-14(19)11(3)21-28-18/h5-8,22H,1-4H3,(H,20,23)
PubChem CID	10185556
ChEMBL	CHEMBL304460
IUPHAR	N/A
BindingDB	50143797
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37311	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
37312	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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