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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL300066
Molecular formula	C24H27N3O4S2
IUPAC name	4-tert-butyl-N-[5-(3-cyanopropyl)-4-(3-methoxyphenyl)sulfanyl-1,2-oxazol-3-yl]benzenesulfonamide
Molecular weight	485.617
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.3
Synonyms	3-(4-tert-Butylphenylsulfonylamino)-4-(3-methoxyphenylthio)isoxazole-5-butanenitrile BDBM50091539 4-tert-Butyl-N-[5-(3-cyano-propyl)-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-benzenesulfonamide
Inchi Key	CAWAINHZBODTLN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27N3O4S2/c1-24(2,3)17-11-13-20(14-12-17)33(28,29)27-23-22(21(31-26-23)10-5-6-15-25)32-19-9-7-8-18(16-19)30-4/h7-9,11-14,16H,5-6,10H2,1-4H3,(H,26,27)
PubChem CID	44298343
ChEMBL	CHEMBL300066
IUPHAR	N/A
BindingDB	50091539
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37578	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
37579	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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