You can:
| Name | Endothelin receptor type B |
|---|---|
| Species | Sus scrofa (Pig) |
| Gene | EDNRB |
| Synonym | Endothelin receptor non-selective type ET-B ET-BR |
| Disease | N/A for non-human GPCRs |
| Length | 443 |
| Amino acid sequence | MQPLRSLCGRALVALIFACGVAGVQSEERGFPPAGATPPALRTGEIVAPPTKTFWPRGSNASLPRSSSPPQMPKGGRMAGPPARTLTPPPCEGPIEIKDTFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINVYKLLAEDWPFGVEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEALGFDMITTDYKGNRLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQNDSNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS |
| UniProt | P35463 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3949 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 843 |  CHEMBL96847 | C26H29N3O6S | 511.593 | 7 / 1 | 4.1 | No |
| 1507 |  CHEMBL326861 | C27H36N2O7S | 532.652 | 9 / 1 | 1.4 | No |
| 1747 |  CHEMBL94918 | C24H25N3O6S | 483.539 | 7 / 1 | 3.3 | Yes |
| 2361 |  CHEMBL109736 | C26H32N2O5 | 452.551 | 6 / 1 | 1.0 | Yes |
| 3376 |  CHEMBL9139 | C27H34N2O6 | 482.577 | 7 / 1 | 1.7 | Yes |
| 3687 |  CHEMBL72891 | C31H46BrN5O5S | 680.703 | 6 / 5 | 6.0 | No |
| 4113 |  CHEMBL326191 | C30H40N2O5 | 508.659 | 6 / 1 | 2.6 | No |
| 4572 |  CHEMBL9082 | C25H29NO6 | 439.508 | 7 / 1 | 1.5 | Yes |
| 4576 |  CHEMBL2304007 | C33H44N6O7 | 636.75 | 7 / 6 | 2.7 | No |
| 6577 |  CHEMBL9141 | C24H28N2O6 | 440.496 | 7 / 2 | 0.6 | Yes |
| 6865 |  CHEMBL368255 | C30H41N5O5 | 551.688 | 6 / 4 | 5.0 | No |
| 9302 |  CHEMBL176992 | C30H41N5O4S | 567.749 | 6 / 4 | 5.6 | No |
| 11197 |  CHEMBL266337 | C25H30N2O6 | 454.523 | 7 / 2 | 1.0 | Yes |
| 11377 |  CHEMBL266143 | C26H26N2O5 | 446.503 | 7 / 1 | 1.3 | Yes |
| 12263 |  CHEMBL293702 | C22H22O6 | 382.412 | 6 / 1 | 4.5 | Yes |
| 12376 |  CHEMBL65292 | C27H32O7 | 468.546 | 7 / 1 | 6.3 | No |
| 12852 |  BDBM50287884 | C73H97N15O21 | 1520.66 | 22 / 19 | 2.3 | No |
| 13535 |  CHEMBL176093 | C29H39N5O5 | 537.661 | 6 / 4 | 3.8 | No |
| 13612 |  CHEMBL172543 | C33H40N6O5 | 600.72 | 7 / 3 | 4.3 | No |
| 14300 |  CHEMBL299328 | C27H21N2O8S- | 533.531 | 11 / 0 | 5.2 | No |
| 14993 |  CHEMBL172506 | C34H42N6O5 | 614.747 | 7 / 3 | 4.6 | No |
| 15196 |  CHEMBL77083 | C31H45N5O5 | 567.731 | 5 / 5 | 4.7 | No |
| 18446 |  CHEMBL367208 | C29H34N6O4 | 530.629 | 5 / 5 | 4.0 | No |
| 18965 |  CHEMBL426413 | C30H40N6O4 | 548.688 | 5 / 5 | 4.2 | No |
| 19172 |  CHEMBL61211 | C27H24O7 | 460.482 | 7 / 1 | 4.9 | Yes |
| 19177 |  CHEMBL264543 | C27H24O7 | 460.482 | 7 / 1 | 4.9 | Yes |
| 19179 |  CHEMBL62395 | C27H24O7 | 460.482 | 7 / 1 | 4.9 | Yes |
| 20896 |  CHEMBL342615 | C30H42N6O8S | 646.76 | 8 / 6 | 1.6 | No |
| 22516 |  CHEMBL2304014 | C31H39N7O7 | 621.695 | 8 / 6 | 1.9 | No |
| 22904 |  CHEMBL308621 | C32H45N7O5 | 607.756 | 6 / 6 | 4.0 | No |
| 24153 |  CHEMBL113379 | C26H32N2O5 | 452.551 | 6 / 1 | 1.0 | Yes |
| 25489 |  CHEMBL8925 | C28H36N2O6 | 496.604 | 6 / 1 | 4.6 | Yes |
| 27641 |  CHEMBL419367 | C28H34F4N2O7S | 618.641 | 13 / 1 | 2.5 | No |
| 28477 |  CID 44314819 | C73H97N15O21 | 1520.66 | 22 / 19 | 2.3 | No |
| 28648 |  CHEMBL8677 | C27H27NO6 | 461.514 | 7 / 1 | 2.0 | Yes |
| 30606 |  CHEMBL77853 | C30H42BrN5O5 | 632.6 | 5 / 5 | 5.6 | No |
| 30927 |  CHEMBL323789 | C28H38N2O7S | 546.679 | 9 / 1 | 1.9 | No |
| 31792 |  CHEMBL9334 | C28H36N2O6 | 496.604 | 7 / 1 | 2.0 | Yes |
| 32516 |  CHEMBL418667 | C21H20O6 | 368.385 | 6 / 1 | 3.9 | Yes |
| 33549 |  CHEMBL133257 | C33H44N6O7 | 636.75 | 7 / 6 | 2.7 | No |
| 33906 |  CHEMBL331577 | C25H32N2O5 | 440.54 | 6 / 1 | 0.9 | Yes |
| 34514 |  CHEMBL96644 | C25H25N3O6S | 495.55 | 7 / 1 | 3.2 | Yes |
| 34701 |  CHEMBL368461 | C29H32FN5O5 | 549.603 | 7 / 4 | 4.4 | No |
| 34786 |  CHEMBL366544 | C30H42N6O4 | 550.704 | 5 / 5 | 4.7 | No |
| 37578 |  CHEMBL300066 | C24H27N3O4S2 | 485.617 | 8 / 1 | 5.3 | No |
| 37590 |  CHEMBL174818 | C31H41N5O7 | 595.697 | 8 / 4 | 4.2 | No |
| 40427 |  CHEMBL368853 | C29H32FN5O5 | 549.603 | 7 / 4 | 4.4 | No |
| 40804 |  CHEMBL417050 | C24H18O6 | 402.402 | 6 / 1 | 4.2 | Yes |
| 44689 |  CHEMBL74471 | C36H45BrN6O5 | 721.697 | 5 / 6 | 6.5 | No |
| 45931 |  CHEMBL62450 | C31H24O7 | 508.526 | 7 / 1 | 5.6 | No |
| 46727 |  CHEMBL48907 | C27H23N2NaO7S | 542.538 | 10 / 0 | N/A | No |
| 48261 |  CHEMBL427935 | C21H22N2O6 | 398.415 | 7 / 2 | -0.7 | Yes |
| 49383 |  CHEMBL112832 | C30H38N2O5 | 506.643 | 6 / 1 | 3.0 | No |
| 49577 |  CHEMBL9212 | C25H30N2O6 | 454.523 | 7 / 1 | 0.6 | Yes |
| 51240 |  CHEMBL177195 | C30H41N5O5 | 551.688 | 6 / 4 | 4.8 | No |
| 51484 |  CHEMBL299572 | C27H23N2NaO7S | 542.538 | 10 / 0 | N/A | No |
| 53873 |  CHEMBL415762 | C27H37N5O6S | 559.682 | 9 / 4 | 3.8 | No |
| 54344 |  CHEMBL77033 | C30H44BrN5O5 | 634.616 | 5 / 5 | 5.7 | No |
| 54464 |  CHEMBL113087 | C31H36N2O7S | 580.696 | 9 / 1 | 2.5 | No |
| 56036 |  CHEMBL287888 | C33H51N5O5 | 597.801 | 5 / 5 | 6.0 | No |
| 56038 |  CHEMBL405724 | C33H51N5O5 | 597.801 | 5 / 5 | 6.0 | No |
| 58767 |  CHEMBL113611 | C30H40N2O6 | 524.658 | 7 / 1 | 2.3 | No |
| 58814 |  CHEMBL9283 | C31H34N2O6 | 530.621 | 7 / 1 | 2.7 | No |
| 60464 |  CHEMBL65201 | C29H28O6 | 472.537 | 6 / 1 | 6.1 | No |
| 61080 |  CHEMBL8878 | C25H31NO6 | 441.524 | 7 / 1 | 1.5 | Yes |
| 62825 |  CHEMBL2304018 | C30H39ClN6O7 | 631.127 | 7 / 6 | 2.8 | No |
| 63066 |  CHEMBL323055 | C28H37FN2O7S | 564.669 | 10 / 1 | 2.0 | No |
| 64026 |  CHEMBL311134 | C31H41N7O5 | 591.713 | 6 / 6 | 3.0 | No |
| 64385 |  CHEMBL112325 | C26H34N2O6 | 470.566 | 7 / 1 | 0.9 | Yes |
| 64494 |  CHEMBL9119 | C26H32N2O6 | 468.55 | 7 / 1 | 1.2 | Yes |
| 65490 |  CHEMBL109242 | C31H44N2O7S | 588.76 | 9 / 1 | 3.2 | No |
| 67158 |  CHEMBL418898 | C21H20N2O3 | 348.402 | 3 / 3 | 2.3 | Yes |
| 67875 |  CHEMBL64447 | C25H26O7 | 438.476 | 7 / 1 | 4.9 | Yes |
| 69356 |  CHEMBL312541 | C33H42N6O7 | 634.734 | 7 / 6 | 2.1 | No |
| 71306 |  CHEMBL52338 | C28H25N2NaO5S | 524.567 | 8 / 0 | N/A | No |
| 73572 |  CHEMBL367989 | C30H41N5O5 | 551.688 | 6 / 4 | 4.9 | No |
| 75038 |  Sulfiodizole | C10H10IN3O3S | 379.172 | 6 / 2 | 1.6 | Yes |
| 76414 |  CHEMBL114084 | C26H32N2O6 | 468.55 | 7 / 1 | 0.7 | Yes |
| 78775 |  CHEMBL176514 | C31H35N5O5 | 557.651 | 6 / 3 | 4.5 | No |
| 81300 |  CHEMBL113529 | C29H40N2O5 | 496.648 | 6 / 1 | 2.5 | Yes |
| 81805 |  CHEMBL65353 | C25H26O6 | 422.477 | 6 / 1 | 5.3 | No |
| 82769 |  CHEMBL172760 | C34H41N5O4S | 615.793 | 6 / 4 | 6.3 | No |
| 84069 |  CHEMBL9050 | C27H34N2O6 | 482.577 | 7 / 1 | 1.7 | Yes |
| 84517 |  CHEMBL48907 | C27H23N2O7S- | 519.548 | 10 / 0 | 5.3 | No |
| 85205 |  CHEMBL62762 | C25H28O7 | 440.492 | 7 / 1 | 5.3 | No |
| 86173 |  CHEMBL293012 | C25H22O6S | 450.505 | 7 / 1 | 5.1 | No |
| 86291 |  CHEMBL62374 | C20H17ClO6 | 388.8 | 6 / 1 | 4.1 | Yes |
| 89349 |  CHEMBL63121 | C21H20O7 | 384.384 | 7 / 1 | 3.5 | Yes |
| 89352 |  CHEMBL65070 | C21H20O7 | 384.384 | 7 / 1 | 3.5 | Yes |
| 90079 |  CHEMBL9012 | C26H24FNO5 | 449.478 | 7 / 1 | 1.9 | Yes |
| 91697 |  CHEMBL51234 | C27H22ClN2O7S- | 553.99 | 10 / 0 | 6.0 | No |
| 92641 |  CHEMBL55664 | C22H26N2O4S2 | 446.58 | 7 / 1 | 5.8 | No |
| 93821 |  CHEMBL175277 | C33H43N5O5 | 589.737 | 6 / 4 | 5.4 | No |
| 97122 |  CHEMBL171910 | C30H41N5O5 | 551.688 | 6 / 4 | 4.9 | No |
| 98071 |  CHEMBL176565 | C29H40N6O4 | 536.677 | 5 / 4 | 3.9 | No |
| 98482 |  CHEMBL111769 | C26H34N2O7S | 518.625 | 9 / 1 | 0.9 | No |
| 100281 |  CHEMBL64726 | C27H24O7 | 460.482 | 7 / 1 | 5.0 | Yes |
| 101362 |  CHEMBL62264 | C24H26O6 | 410.466 | 6 / 1 | 5.2 | No |
| 101364 |  CHEMBL64832 | C24H26O6 | 410.466 | 6 / 1 | 5.2 | No |
| 102026 |  CHEMBL48411 | C27H23N2NaO7S | 542.538 | 10 / 0 | N/A | No |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417