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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL112325
Molecular formula	C26H34N2O6
IUPAC name	(2R,3R,4S)-4-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)-1-[2-[methyl(propyl)amino]-2-oxoethyl]pyrrolidine-3-carboxylic acid
Molecular weight	470.566
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	0.9
Synonyms	BDBM50056059 (2R,3R,4S)-4-(2,4-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid
Inchi Key	DNIGUSWIAUIEJP-SDUSCBPUSA-N
Inchi ID	InChI=1S/C26H34N2O6/c1-6-13-27(2)23(29)16-28-15-21(20-12-11-19(33-4)14-22(20)34-5)24(26(30)31)25(28)17-7-9-18(32-3)10-8-17/h7-12,14,21,24-25H,6,13,15-16H2,1-5H3,(H,30,31)/t21-,24-,25+/m1/s1
PubChem CID	10814222
ChEMBL	CHEMBL112325
IUPHAR	N/A
BindingDB	50056059
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
64385	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
64384	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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