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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL427935
Molecular formula	C21H22N2O6
IUPAC name	(2S,3S,4R)-1-(2-amino-2-oxoethyl)-4-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
Molecular weight	398.415
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	-0.7
Synonyms	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-carbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid BDBM50051010
Inchi Key	CQNUXGPALBHTAC-RYGJVYDSSA-N
Inchi ID	InChI=1S/C21H22N2O6/c1-27-14-5-2-12(3-6-14)20-19(21(25)26)15(9-23(20)10-18(22)24)13-4-7-16-17(8-13)29-11-28-16/h2-8,15,19-20H,9-11H2,1H3,(H2,22,24)(H,25,26)/t15-,19-,20+/m0/s1
PubChem CID	11795139
ChEMBL	CHEMBL427935
IUPHAR	N/A
BindingDB	50051010
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
48261	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
48262	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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