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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL177195
Molecular formula	C30H41N5O5
IUPAC name	5-methyl-2-[(1R)-2-(1-methylindol-3-yl)-1-[[(2S)-4-methyl-2-[(4-methylcyclohexyl)carbamoylamino]pentanoyl]amino]ethyl]-1,3-oxazole-4-carboxylic acid
Molecular weight	551.688
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	4.8
Synonyms	BDBM50050048 SCHEMBL9113948 5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-4-methyl-2-[3-(4-methyl-cyclohexyl)-ureido]-pentanoylamino}-ethyl)-oxazole-4-carboxylic acid
Inchi Key	CUXQJQJNEAEYGC-NWOKVLSISA-N
Inchi ID	InChI=1S/C30H41N5O5/c1-17(2)14-23(33-30(39)31-21-12-10-18(3)11-13-21)27(36)32-24(28-34-26(29(37)38)19(4)40-28)15-20-16-35(5)25-9-7-6-8-22(20)25/h6-9,16-18,21,23-24H,10-15H2,1-5H3,(H,32,36)(H,37,38)(H2,31,33,39)/t18?,21?,23-,24+/m0/s1
PubChem CID	10554724
ChEMBL	CHEMBL177195
IUPHAR	N/A
BindingDB	50050048
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51240	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
51241	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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