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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL175277
Molecular formula	C33H43N5O5
IUPAC name	2-[(1R)-1-[[(2S)-2-(1-adamantylcarbamoylamino)-4-methylpentanoyl]amino]-2-(1-methylindol-3-yl)ethyl]-5-methyl-1,3-oxazole-4-carboxylic acid
Molecular weight	589.737
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	5.4
Synonyms	SCHEMBL9110212 2-[(R)-1-[(S)-2-(3-Adamantan-1-yl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid BDBM50050021
Inchi Key	GDOJAPBZYKAXMB-CZAVTBICSA-N
Inchi ID	InChI=1S/C33H43N5O5/c1-18(2)9-25(35-32(42)37-33-14-20-10-21(15-33)12-22(11-20)16-33)29(39)34-26(30-36-28(31(40)41)19(3)43-30)13-23-17-38(4)27-8-6-5-7-24(23)27/h5-8,17-18,20-22,25-26H,9-16H2,1-4H3,(H,34,39)(H,40,41)(H2,35,37,42)/t20?,21?,22?,25-,26+,33?/m0/s1
PubChem CID	10841134
ChEMBL	CHEMBL175277
IUPHAR	N/A
BindingDB	50050021
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
93821	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
93820	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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