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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL174818
Molecular formula	C31H41N5O7
IUPAC name	2-[(1R)-1-[[(2S)-2-[(1-methoxycarbonylcyclohexyl)carbamoylamino]-4-methylpentanoyl]amino]-2-(1-methylindol-3-yl)ethyl]-5-methyl-1,3-oxazole-4-carboxylic acid
Molecular weight	595.697
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	4.2
Synonyms	BDBM50050010 SCHEMBL9113915 2-[(R)-1-{(S)-2-[3-(1-Methoxycarbonyl-cyclohexyl)-ureido]-4-methyl-pentanoylamino}-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid
Inchi Key	CAWORLTZNUHRES-XZOQPEGZSA-N
Inchi ID	InChI=1S/C31H41N5O7/c1-18(2)15-22(33-30(41)35-31(29(40)42-5)13-9-6-10-14-31)26(37)32-23(27-34-25(28(38)39)19(3)43-27)16-20-17-36(4)24-12-8-7-11-21(20)24/h7-8,11-12,17-18,22-23H,6,9-10,13-16H2,1-5H3,(H,32,37)(H,38,39)(H2,33,35,41)/t22-,23+/m0/s1
PubChem CID	10627333
ChEMBL	CHEMBL174818
IUPHAR	N/A
BindingDB	50050010
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37590	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
37589	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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