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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Endothelin receptor type B
Species	Sus scrofa (Pig)
Gene	EDNRB
Synonym	Endothelin receptor non-selective type ET-B ET-BR
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MQPLRSLCGRALVALIFACGVAGVQSEERGFPPAGATPPALRTGEIVAPPTKTFWPRGSNASLPRSSSPPQMPKGGRMAGPPARTLTPPPCEGPIEIKDTFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINVYKLLAEDWPFGVEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEALGFDMITTDYKGNRLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQNDSNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
UniProt	P35463
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3949
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Sulfiodizole
Molecular formula	C10H10IN3O3S
IUPAC name	4-amino-N-(4-iodo-5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
Molecular weight	379.172
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	1.6
Synonyms	4-Iodo-5-methyl-3-sulfanilamidoisoxazole AC1Q4PLV Sulfanilamide, N(sup 1)-(4-iodo-5-methyl-3-isoxazolyl)- 4-amino-n-(4-iodo-5-methyl-1,2-oxazol-3-yl)benzenesulfonamide Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)- CHEMBL298976 AKOS030586380 4-Amino-N-(4-iodo-5-methyl-isoxazol-3-yl)-benzenesulfonamide BRN 0808571 AC1L3QZM LS-147799 BDBM50091532 [ Show all ]
Inchi Key	FCLGWHGVNGNUQT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H10IN3O3S/c1-6-9(11)10(13-17-6)14-18(15,16)8-4-2-7(12)3-5-8/h2-5H,12H2,1H3,(H,13,14)
PubChem CID	120533
ChEMBL	CHEMBL298976
IUPHAR	N/A
BindingDB	50091532
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<1000000.0 nM	PMID10969989	BindingDB,ChEMBL

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