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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL92965
Molecular formula	C27H25NO4S
IUPAC name	4-(2-methylphenyl)-4-[2-pyridin-2-yl-5-(thiophen-3-ylmethoxy)phenoxy]butanoic acid
Molecular weight	459.56
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.4
Synonyms	4-[2-(2-Pyridyl)-5-(3-thienylmethoxy)phenoxy]-4-(2-methylphenyl)butyric acid BDBM50065520 SCHEMBL7907773 4-[2-Pyridin-2-yl-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid
Inchi Key	BRFPHZRJHAJJMA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H25NO4S/c1-19-6-2-3-7-22(19)25(11-12-27(29)30)32-26-16-21(31-17-20-13-15-33-18-20)9-10-23(26)24-8-4-5-14-28-24/h2-10,13-16,18,25H,11-12,17H2,1H3,(H,29,30)
PubChem CID	10504148
ChEMBL	CHEMBL92965
IUPHAR	N/A
BindingDB	50065520
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30944	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
30945	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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