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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL315280
Molecular formula	C27H21ClN2O7
IUPAC name	2-[[2-(carboxymethoxy)phenyl]methyl]-4-[(6-chloro-1,3-benzodioxol-5-yl)methyl]-5-phenylpyrazole-3-carboxylic acid
Molecular weight	520.922
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.3
Synonyms	2-(2-Carboxymethoxy-benzyl)-4-(6-chloro-benzo[1,3]dioxol-5-ylmethyl)-5-phenyl-2H-pyrazole-3-carboxylic acid BDBM50093984
Inchi Key	AHXPDBYIMNNPOY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H21ClN2O7/c28-20-12-23-22(36-15-37-23)11-18(20)10-19-25(16-6-2-1-3-7-16)29-30(26(19)27(33)34)13-17-8-4-5-9-21(17)35-14-24(31)32/h1-9,11-12H,10,13-15H2,(H,31,32)(H,33,34)
PubChem CID	44320212
ChEMBL	CHEMBL315280
IUPHAR	N/A
BindingDB	50093984
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5963	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
5962	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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