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| Name | fMet-Leu-Phe receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | FPR1 |
| Synonym | NFPR N-formylpeptide chemoattractant receptor N-formyl peptide receptor FPR1 FPR [ Show all ] |
| Disease | Inflammatory disease Peptic ulcer |
| Length | 350 |
| Amino acid sequence | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK |
| UniProt | P21462 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P21462 |
| 3D structure model | This predicted structure model is from GPCR-EXP P21462. |
| BioLiP | N/A |
| Therapeutic Target Database | T87831 |
| ChEMBL | CHEMBL3359 |
| IUPHAR | 222 |
| DrugBank | BE0000995 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 497 |  CHEMBL2391280 | C20H17BrFN3O2 | 430.277 | 4 / 1 | 3.4 | Yes |
| 2140 |  cid_654635 | C25H23NO6 | 433.46 | 6 / 1 | 3.8 | Yes |
| 441769 |  CHEMBL3311132 | C44H58ClN5O8 | 820.425 | 8 / 6 | 7.2 | No |
| 4406 |  UNM000003539401 | C23H15F3O7 | 460.361 | 10 / 0 | 4.8 | Yes |
| 4740 |  MLS000045863 | C19H16FN3O2 | 337.354 | 4 / 1 | 2.7 | Yes |
| 463467 |  AC1MHCQD | C25H24N2O5 | 432.476 | 6 / 1 | 4.1 | Yes |
| 5876 |  diamide 7 | C22H22N2O3S | 394.489 | 4 / 3 | 4.8 | Yes |
| 6288 |  CHEMBL554291 | C23H25N3O5 | 423.469 | 6 / 1 | 2.5 | Yes |
| 6295 |  MLS000118627 | C23H20N6O3S2 | 492.572 | 8 / 1 | 3.8 | Yes |
| 6364 |  methionine benzimidazole 6 | C23H25N3O3S | 423.531 | 5 / 2 | 4.8 | Yes |
| 6568 |  CHEMBL1770303 | C21H17ClN2O3 | 380.828 | 3 / 3 | 4.6 | Yes |
| 6790 |  BDBM37655 | C22H17BrN2O4 | 453.292 | 5 / 0 | 4.2 | Yes |
| 7081 |  CHEMBL2391452 | C20H18BrN3O3 | 428.286 | 4 / 1 | 3.0 | Yes |
| 7715 |  SMR000055040 | C19H16O6 | 340.331 | 6 / 0 | 3.5 | Yes |
| 9473 |  MLS000046638 | C21H32N2O3S | 392.558 | 4 / 0 | 3.1 | Yes |
| 9498 |  SMR000064011 | C13H10N2O2S2 | 290.355 | 5 / 1 | 2.7 | Yes |
| 10128 |  4-(3-methoxyphenyl)-2-phenyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one | C19H15N3O2 | 317.348 | 4 / 1 | 3.8 | Yes |
| 10134 |  UNM000003612901 | C20H19NO2S | 337.437 | 3 / 1 | 2.7 | Yes |
| 10223 |  5-(2,4-dimethoxyphenyl)-3-hydroxy-1-(2-morpholin-4-ylethyl)-4-(thien-2-ylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one | C23H26N2O6S | 458.529 | 8 / 1 | 2.6 | Yes |
| 464160 |  3-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-5-(2-thienyl)-4-(2-thienylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one | C17H17NO5S2 | 379.445 | 7 / 2 | 1.9 | Yes |
| 11391 |  CHEMBL1916285 | C28H37N5O4S | 539.695 | 7 / 2 | 4.6 | No |
| 12178 |  MLS000117271 | C25H27N3O2S | 433.57 | 5 / 0 | 4.8 | Yes |
| 12994 |  cid_664130 | C21H25N3O5S | 431.507 | 8 / 0 | 1.8 | Yes |
| 13259 |  CHEMBL2391437 | C18H16BrN3O2S | 418.309 | 4 / 1 | 3.0 | Yes |
| 13466 |  CHEMBL1934421 | C25H36F3N5O3S | 543.65 | 9 / 2 | 5.4 | No |
| 13946 |  4-Aminodiphenylamine | C12H12N2 | 184.242 | 2 / 2 | 2.5 | Yes |
| 13951 |  BDBM37716 | C14H14N4OS2 | 318.413 | 6 / 2 | 2.5 | Yes |
| 14524 |  MLS000045459 | C18H16N4O4S | 384.41 | 9 / 1 | 4.0 | Yes |
| 14771 |  BDBM50026604 | C23H20N2O3S | 404.484 | 5 / 1 | 4.0 | Yes |
| 442288 |  CHEMBL3311300 | C51H67N5O9 | 894.123 | 9 / 6 | 8.8 | No |
| 464890 |  ChemDiv2_004729 | C16H18N4O3 | 314.345 | 6 / 2 | 2.1 | Yes |
| 17068 |  MLS000089738 | C18H21N7O3 | 383.412 | 9 / 1 | 1.5 | Yes |
| 17266 |  SMR000021507 | C23H20FN5O4S | 481.502 | 8 / 2 | 3.1 | Yes |
| 17671 |  CHEMBL1916276 | C24H28N4O3S | 452.573 | 5 / 2 | 5.2 | No |
| 17728 |  UNM000003660701 | C20H14F2N4O2 | 380.355 | 6 / 1 | 3.8 | Yes |
| 17825 |  CHEMBL2372473 | C66H120N12O12 | 1273.76 | 13 / 6 | 7.7 | No |
| 465150 |  845808-35-7 | C25H27N3O5 | 449.507 | 6 / 1 | 3.6 | Yes |
| 465180 |  AC1LDEGG | C19H18N2O5 | 354.362 | 6 / 1 | 1.7 | Yes |
| 19717 |  MLS000086404 | C25H25N3O6 | 463.49 | 9 / 2 | 3.3 | Yes |
| 22492 |  CHEMBL1934414 | C23H34N4O3S | 446.61 | 5 / 2 | 5.0 | Yes |
| 23430 |  Amedin | C18H27NO3 | 305.418 | 4 / 1 | 3.4 | Yes |
| 517458 |  CHEMBL440917 | C16H12N4O2 | 292.298 | 4 / 0 | 1.3 | Yes |
| 24773 |  MLS000116347 | C18H20N2O4S | 360.428 | 6 / 1 | 4.1 | Yes |
| 25386 |  MLS000047151 | C11H10N2O4S2 | 298.331 | 7 / 0 | 1.3 | Yes |
| 30465 |  BDBM37823 | C22H18N2O5 | 390.395 | 6 / 0 | 1.9 | Yes |
| 558228 |  CHEMBL433815 | C19H18N4O | 318.38 | 3 / 2 | 2.6 | Yes |
| 31209 |  BDBM37731 | C16H18N4O3 | 314.345 | 6 / 2 | 2.0 | Yes |
| 31638 |  MLS000057035 | C21H15N5O | 353.385 | 4 / 1 | 3.6 | Yes |
| 31910 |  Hyoscine methonitrate | C18H24N2O7 | 380.397 | 7 / 1 | N/A | N/A |
| 32586 |  BDBM40407 | C23H25NO4 | 379.456 | 4 / 0 | 3.4 | Yes |
| 442975 |  CHEMBL3311035 | C38H55N5O8 | 709.885 | 8 / 6 | 5.0 | No |
| 553427 |  Spinorphin | C45H64N8O10 | 877.053 | 11 / 10 | 1.0 | No |
| 35284 |  BDBM40424 | C24H27NO4 | 393.483 | 4 / 0 | 3.8 | Yes |
| 558356 |  SMR000091904 | C11H16N2O2S | 240.321 | 4 / 1 | 2.2 | Yes |
| 38029 |  BDBM40419 | C25H25N3O5 | 447.491 | 6 / 0 | 2.5 | Yes |
| 443198 |  CHEMBL3311294 | C43H65N5O9 | 796.019 | 9 / 6 | 6.6 | No |
| 38564 |  CHEMBL2391286 | C18H16BrN3O2S | 418.309 | 4 / 1 | 3.0 | Yes |
| 40162 |  AC1MN97W | C24H20N4O4 | 428.448 | 6 / 1 | 2.7 | Yes |
| 41467 |  MLS000117714 | C19H26N2O5S | 394.486 | 6 / 1 | 2.6 | Yes |
| 468048 |  5-[4-(allyloxy)phenyl]-4-(2-furoyl)-3-hydroxy-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one | C24H20N2O5 | 416.433 | 6 / 1 | 3.4 | Yes |
| 41958 |  BDBM40418 | C23H26N2O6S | 458.529 | 8 / 0 | 2.1 | Yes |
| 42052 |  BDBM37707 | C15H17N5 | 267.336 | 5 / 1 | 2.3 | Yes |
| 468222 |  AC1LDEG2 | C20H15BrN2O7 | 475.251 | 8 / 2 | 3.4 | Yes |
| 43300 |  benzimidazole, 5 | C23H24N4O2 | 388.471 | 3 / 1 | 3.9 | Yes |
| 443398 |  CHEMBL3311298 | C51H68N6O10 | 925.137 | 10 / 6 | 8.7 | No |
| 44481 |  MLS000069104 | C17H17N3O3 | 311.341 | 5 / 1 | 1.8 | Yes |
| 44881 |  AC1MEUXL | C23H26N2O7 | 442.468 | 8 / 1 | 2.0 | Yes |
| 45176 |  CHEMBL1934418 | C23H34N4O3S2 | 478.67 | 6 / 2 | 4.9 | Yes |
| 45242 |  CHEMBL562380 | C21H20BrN3O3 | 442.313 | 4 / 1 | 3.3 | Yes |
| 46362 |  UNM000003546901 | C21H10ClF3O5 | 434.751 | 8 / 0 | 5.5 | No |
| 46713 |  CHEMBL2391442 | C22H22IN3O4 | 519.339 | 5 / 1 | 3.2 | No |
| 47866 |  CHEMBL2372474 | C60H107N11O12 | 1174.58 | 12 / 6 | 6.8 | No |
| 47943 |  UNM000003607801 | C18H18N2O4S | 358.412 | 5 / 0 | 2.5 | Yes |
| 48663 |  BDBM40401 | C24H27NO5 | 409.482 | 5 / 1 | 4.4 | Yes |
| 49231 |  CHEMBL560780 | C21H20IN3O3 | 489.313 | 4 / 1 | 3.2 | Yes |
| 49845 |  CHEMBL1916255 | C23H28N4O3S | 440.562 | 5 / 2 | 5.2 | No |
| 469143 |  380589-24-2 | C21H22N2O4S | 398.477 | 6 / 1 | 2.7 | Yes |
| 51466 |  SMR000022571 | C17H18N4O | 294.358 | 3 / 1 | 2.1 | Yes |
| 53057 |  SMR000025325 | C19H19N3O2S | 353.44 | 4 / 1 | 3.8 | Yes |
| 53539 |  CHEMBL2372486 | C63H113N11O14 | 1248.66 | 14 / 9 | 7.1 | No |
| 55278 |  MLS000068716 | C15H15N3O2S2 | 333.424 | 6 / 1 | 2.6 | Yes |
| 55866 |  CHEMBL2391284 | C21H17BrF3N3O2 | 480.285 | 6 / 1 | 4.2 | Yes |
| 56936 |  BDBM40442 | C24H17BrFNO3 | 466.306 | 4 / 0 | 5.2 | No |
| 57178 |  2-N-(4-aminophenyl)benzene-1,2-diamine | C12H13N3 | 199.257 | 3 / 3 | 2.1 | Yes |
| 57946 |  UNM000003607901 | C18H19N3O2 | 309.369 | 4 / 1 | 2.8 | Yes |
| 58537 |  CHEMBL2391276 | C27H24BrN3O3 | 518.411 | 4 / 1 | 4.9 | No |
| 59391 |  MLS000123585 | C15H12N4O | 264.288 | 4 / 1 | 1.9 | Yes |
| 59394 |  BDBM37804 | C23H25NO6 | 411.454 | 6 / 0 | 2.7 | Yes |
| 60156 |  CHEMBL1770475 | C26H24N4OS | 440.565 | 4 / 1 | 4.6 | Yes |
| 60267 |  CHEMBL2391283 | C22H22BrN3O4 | 472.339 | 5 / 1 | 3.3 | Yes |
| 60384 |  2-[(4-bromophenyl)carbamoyl]cyclohexane-1-carboxylic acid | C14H16BrNO3 | 326.19 | 3 / 2 | 2.9 | Yes |
| 61232 |  CHEMBL1916260 | C20H28N4O3S | 404.529 | 5 / 2 | 4.1 | Yes |
| 61391 |  CHEMBL1916087 | C26H26N4O3S | 474.579 | 5 / 2 | 5.2 | No |
| 61408 |  benzimidazole, 13 | C22H21FN4O | 376.435 | 3 / 1 | 4.1 | Yes |
| 559175 |  CHEMBL390200 | C23H25N5O | 387.487 | 4 / 1 | 2.6 | Yes |
| 62356 |  CHEMBL2372498 | C64H115N11O15 | 1278.69 | 15 / 9 | 6.1 | No |
| 470744 |  AC1LCLHZ | C25H23NO6 | 433.46 | 6 / 1 | 4.3 | Yes |
| 63647 |  CHEMBL217053 | C18H13BrN2O4 | 401.216 | 5 / 1 | 3.5 | Yes |
| 63911 |  cid_660196 | C19H12ClN3O4 | 381.772 | 6 / 0 | 2.7 | Yes |
| 64107 |  SMR000026956 | C11H11N3O2S | 249.288 | 4 / 1 | 1.1 | Yes |
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