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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	845808-35-7
Molecular formula	C25H27N3O5
IUPAC name	4-hydroxy-1-(3-imidazol-1-ylpropyl)-3-(5-methylfuran-2-carbonyl)-2-(4-propan-2-yloxyphenyl)-2H-pyrrol-5-one
Molecular weight	449.507
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.6
Synonyms	ST50119122 AKOS002222042 CHEMBL1374204 1-(3-(1H-imidazol-1-yl)propyl)-3-hydroxy-5-(4-isopropoxyphenyl)-4-(5-methylfuran-2-carbonyl)-1H-pyrrol-2(5H)-one MLS001074033 AKOS016304012 VU0605623-1 F3226-1855 3-hydroxy-1-(3-imidazolylpropyl)-4-[(5-methyl(2-furyl))carbonyl]-5-[4-(methyle thoxy)phenyl]-3-pyrrolin-2-one MolPort-000-481-242 AC1LDAFP Z335451150 HMS2472C04 3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-4-(5-methylfuran-2-carbonyl)-5-[4-(propan-2-yloxy)phenyl]-2,5-dihydro-1H-pyrrol-2-one [ Show all ]
Inchi Key	AZXVHGLYSPMUHG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27N3O5/c1-16(2)32-19-8-6-18(7-9-19)22-21(23(29)20-10-5-17(3)33-20)24(30)25(31)28(22)13-4-12-27-14-11-26-15-27/h5-11,14-16,22,30H,4,12-13H2,1-3H3
PubChem CID	663879
ChEMBL	CHEMBL1374204
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
465150	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
18577	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
18578	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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