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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000022571
Molecular formula	C17H18N4O
IUPAC name	2-(4-methylpiperidin-1-yl)-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
Molecular weight	294.358
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.1
Synonyms	2-(4-methylpiperidin-1-yl)-4-oxo-6-phenyl-1H-pyrimidine-5-carbonitrile CHEMBL1387663 4-keto-2-(4-methylpiperidino)-6-phenyl-1H-pyrimidine-5-carbonitrile HMS2385C07 2-(4-methyl-1-piperidinyl)-4-oxo-6-phenyl-1H-pyrimidine-5-carbonitrile BDBM37708 SR-01000120573 cid_3239026 AC1MMHX4 MLS000044627 2-(4-methylpiperidin-1-yl)-4-oxidanylidene-6-phenyl-1H-pyrimidine-5-carbonitrile SR-01000120573-1 4-hydroxy-2-(4-methylpiperidin-1-yl)-6-phenylpyrimidine-5-carbonitrile EU-0089245 AKOS001773326 [ Show all ]
Inchi Key	CVHXUJXFNBZJLC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18N4O/c1-12-7-9-21(10-8-12)17-19-15(13-5-3-2-4-6-13)14(11-18)16(22)20-17/h2-6,12H,7-10H2,1H3,(H,19,20,22)
PubChem CID	135497667
ChEMBL	CHEMBL1387663
IUPHAR	N/A
BindingDB	37708
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51466	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
51465	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351
51464	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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