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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	cid_654635
Molecular formula	C25H23NO6
IUPAC name	5-(4-hydroxy-3-methoxyphenyl)-4-(5-methylfuran-2-carbonyl)-1-(2-phenylethyl)pyrrolidine-2,3-dione
Molecular weight	433.46
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM37626 2-(3-methoxy-4-oxidanyl-phenyl)-3-(5-methylfuran-2-yl)carbonyl-4-oxidanyl-1-(2-phenylethyl)-2H-pyrrol-5-one 4-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(5-methylfuran-2-carbonyl)-1-(2-phenylethyl)-2H-pyrrol-5-one 3-hydroxy-5-(4-hydroxy-3-methoxy-phenyl)-4-(5-methyl-2-furoyl)-1-phenethyl-3-pyrrolin-2-one 4-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(5-methyl-2-furanyl)-oxomethyl]-1-(2-phenylethyl)-2H-pyrrol-5-one
Inchi Key	ADCXOCIGMYJKFP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23NO6/c1-15-8-11-19(32-15)23(28)21-22(17-9-10-18(27)20(14-17)31-2)26(25(30)24(21)29)13-12-16-6-4-3-5-7-16/h3-11,14,21-22,27H,12-13H2,1-2H3
PubChem CID	91896293
ChEMBL	N/A
IUPHAR	N/A
BindingDB	37626
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2140	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
2141	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351

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