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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5-[4-(allyloxy)phenyl]-4-(2-furoyl)-3-hydroxy-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
Molecular formula	C24H20N2O5
IUPAC name	3-(furan-2-carbonyl)-4-hydroxy-2-(4-prop-2-enoxyphenyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one
Molecular weight	416.433
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.4
Synonyms	MLS002540841 STK809954 AKOS000528023 Oprea1_186100 4-(2-furylcarbonyl)-3-hydroxy-5-(4-prop-2-enyloxyphenyl)-1-(3-pyridylmethyl)-3 -pyrrolin-2-one HMS2352M04 SR-01000487368-1 5-[4-(allyloxy)phenyl]-4-(2-furoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1,5-dihydro-2H-pyrrol-2-one AKOS016291042 MolPort-000-426-545 CHEMBL1517647 Oprea1_579354 4-(furan-2-ylcarbonyl)-3-hydroxy-5-[4-(prop-2-en-1-yloxy)phenyl]-1-(pyridin-3-ylmethyl)-1,5-dihydro-2H-pyrrol-2-one MCULE-9686170349 ST50016693 AC1MEZC0 BAS 03305326 NCGC00060319-02 EU-0010845 SR-01000487368 [ Show all ]
Inchi Key	CHDCBILKDYWOOU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H20N2O5/c1-2-12-30-18-9-7-17(8-10-18)21-20(22(27)19-6-4-13-31-19)23(28)24(29)26(21)15-16-5-3-11-25-14-16/h2-11,13-14,21,28H,1,12,15H2
PubChem CID	2911378
ChEMBL	CHEMBL1517647
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
468048	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350

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