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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	fMet-Leu-Phe receptor
Species	Homo sapiens (Human)
Gene	FPR1
Synonym	NFPR N-formylpeptide chemoattractant receptor N-formyl peptide receptor FPR1 FPR formyl peptide receptor 1 fMLP receptor fMLF-R [ Show all ]
Disease	Inflammatory disease Peptic ulcer
Length	350
Amino acid sequence	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
UniProt	P21462
Protein Data Bank	N/A
GPCR-HGmod model	P21462
3D structure model	This predicted structure model is from GPCR-EXP P21462.
BioLiP	N/A
Therapeutic Target Database	T87831
ChEMBL	CHEMBL3359
IUPHAR	222
DrugBank	BE0000995

Ligand

Name	CHEMBL390200
Molecular formula	C23H25N5O
IUPAC name	(4-benzylpiperazin-1-yl)-(2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)methanone
Molecular weight	387.487
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.6
Synonyms	(4-benzylpiperazin-1-yl)(2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)methanone BDBM50211791
Inchi Key	DJHMATLRCWOTQH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25N5O/c29-23(27-13-11-26(12-14-27)16-18-7-3-1-4-8-18)20-15-24-28-17-21(25-22(20)28)19-9-5-2-6-10-19/h1-10,15,21,25H,11-14,16-17H2
PubChem CID	136118022
ChEMBL	CHEMBL390200
IUPHAR	N/A
BindingDB	50211791
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID17475488	BindingDB,ChEMBL

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