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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	380589-24-2
Molecular formula	C21H22N2O4S
IUPAC name	4-hydroxy-1-(2-morpholin-4-ylethyl)-2-phenyl-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
Molecular weight	398.477
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.7
Synonyms	F0916-2990 SR-01000486777-1 AKOS016295042 MLS002540800 CHEMBL1417897 Oprea1_432890 3-hydroxy-1-[2-(morpholin-4-yl)ethyl]-5-phenyl-4-(thiophen-2-ylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one HMS2352A13 STK794418 AC1MEW3A BAS 03302617 MolPort-000-433-719 3-Hydroxy-1-(2-morpholin-4-yl-ethyl)-5-phenyl-4-(thiophene-2-carbonyl)-1,5-dihyd EU-0010775 SR-01000486777 3-hydroxy-1-[2-(morpholin-4-yl)ethyl]-5-phenyl-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one MCULE-1358080274 Z57239907 AKOS001650901 MolPort-000-834-424 3-hydroxy-1-(2-morpholinoethyl)-5-phenyl-4-(thiophene-2-carbonyl)-1H-pyrrol-2(5H)-one [ Show all ]
Inchi Key	CTYNBVVBUYNCFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22N2O4S/c24-19(16-7-4-14-28-16)17-18(15-5-2-1-3-6-15)23(21(26)20(17)25)9-8-22-10-12-27-13-11-22/h1-7,14,18,25H,8-13H2
PubChem CID	2909953
ChEMBL	CHEMBL1417897
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
469143	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350

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