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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	fMet-Leu-Phe receptor
Species	Homo sapiens (Human)
Gene	FPR1
Synonym	NFPR N-formylpeptide chemoattractant receptor N-formyl peptide receptor FPR1 FPR formyl peptide receptor 1 fMLP receptor fMLF-R [ Show all ]
Disease	Inflammatory disease Peptic ulcer
Length	350
Amino acid sequence	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
UniProt	P21462
Protein Data Bank	N/A
GPCR-HGmod model	P21462
3D structure model	This predicted structure model is from GPCR-EXP P21462.
BioLiP	N/A
Therapeutic Target Database	T87831
ChEMBL	CHEMBL3359
IUPHAR	222
DrugBank	BE0000995

Ligand

Name	CHEMBL2372473
Molecular formula	C66H120N12O12
IUPAC name	(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-12-(4-aminobutyl)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular weight	1273.76
Hydrogen bond acceptor	13
Hydrogen bond donor	6
XlogP	7.7
Synonyms	BDBM50026940
Inchi Key	AYVHYWIWAWDDDT-JDHQUYPXSA-N
Inchi ID	InChI=1S/C66H120N12O12/c1-24-26-27-30-44(15)56(80)55-60(84)69-46(25-2)61(85)72(17)37-52(79)73(18)48(33-38(3)4)59(83)71-53(42(11)12)65(89)74(19)49(34-39(5)6)58(82)68-45(16)57(81)70-47(31-28-29-32-67)62(86)75(20)50(35-40(7)8)63(87)76(21)51(36-41(9)10)64(88)77(22)54(43(13)14)66(90)78(55)23/h26-27,38-51,53-56,80H,24-25,28-37,67H2,1-23H3,(H,68,82)(H,69,84)(H,70,81)(H,71,83)/b27-26+/t44-,45+,46+,47-,48-,49-,50+,51+,53-,54+,55+,56-/m1/s1
PubChem CID	73350275
ChEMBL	CHEMBL2372473
IUPHAR	N/A
BindingDB	50026940
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC20	0.5 uM	PMID12361388	ChEMBL
IC50	6300.0 nM	PMID12361388	BindingDB,ChEMBL

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