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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LDEGG
Molecular formula	C19H18N2O5
IUPAC name	3-(furan-2-carbonyl)-4-hydroxy-1-(oxolan-2-ylmethyl)-2-pyridin-3-yl-2H-pyrrol-5-one
Molecular weight	354.362
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.7
Synonyms	AKOS000570571 MolPort-002-001-779 CCG-21636 4-(Furan-2-carbonyl)-3-hydroxy-5-pyridin-3-yl-1-(tetrahydro-furan-2-ylmethyl)-1, HMS2340J17 AKOS022003404 UNM000003576001 MCULE-4898757898 BAS 05541673 CHEMBL1535358 [ Show all ]
Inchi Key	BAFMZRSIUKAOJC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H18N2O5/c22-17(14-6-3-9-26-14)15-16(12-4-1-7-20-10-12)21(19(24)18(15)23)11-13-5-2-8-25-13/h1,3-4,6-7,9-10,13,16,23H,2,5,8,11H2
PubChem CID	646794
ChEMBL	CHEMBL1535358
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
465180	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
18817	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
18818	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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