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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000117271
Molecular formula	C25H27N3O2S
IUPAC name	3-cyclohexyl-8-(2-methoxynaphthalen-1-yl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile
Molecular weight	433.57
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.8
Synonyms	CHEMBL1441874 3-cyclohexyl-8-(2-methoxynaphthalen-1-yl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile AKOS001811512 MCULE-6200054753 CCG-132193 SMR000094223 3-cyclohexyl-8-(2-methoxy-1-naphthyl)-6-oxo-3,4,7,8-tetrahydro-2H,6H-pyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile cid_5307697 AKOS022040907 3-cyclohexyl-6-keto-8-(2-methoxy-1-naphthyl)-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile 3-cyclohexyl-8-(2-methoxynaphthalen-1-yl)-6-oxidanylidene-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile HMS2240N05 AC1NSD3G BDBM34503 MLS001367660 3-cyclohexyl-8-(2-methoxy-1-naphthalenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile [ Show all ]
Inchi Key	AQXJFHKCXZSEEY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27N3O2S/c1-30-22-12-11-17-7-5-6-10-19(17)24(22)20-13-23(29)28-15-27(18-8-3-2-4-9-18)16-31-25(28)21(20)14-26/h5-7,10-12,18,20H,2-4,8-9,13,15-16H2,1H3
PubChem CID	5307697
ChEMBL	CHEMBL1441874
IUPHAR	N/A
BindingDB	34503
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12178	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
12177	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351
12179	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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