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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	fMet-Leu-Phe receptor
Species	Homo sapiens (Human)
Gene	FPR1
Synonym	NFPR N-formylpeptide chemoattractant receptor N-formyl peptide receptor FPR1 FPR formyl peptide receptor 1 fMLP receptor fMLF-R [ Show all ]
Disease	Inflammatory disease Peptic ulcer
Length	350
Amino acid sequence	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
UniProt	P21462
Protein Data Bank	N/A
GPCR-HGmod model	P21462
3D structure model	This predicted structure model is from GPCR-EXP P21462.
BioLiP	N/A
Therapeutic Target Database	T87831
ChEMBL	CHEMBL3359
IUPHAR	222
DrugBank	BE0000995

Ligand

Name	SMR000091904
Molecular formula	C11H16N2O2S
IUPAC name	2-butylsulfanyl-6-hydroxy-3-prop-2-enylpyrimidin-4-one
Molecular weight	240.321
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.2
Synonyms	CHEMBL1624600 STL446402 2-butylsulfanyl-6-oxidanyl-1-prop-2-enyl-pyrimidin-4-one AKOS001695199 MCULE-1813375053 1-allyl-2-(butylthio)-6-hydroxy-4(1H)-pyrimidinone MolPort-004-971-205 2-(butylthio)-6-hydroxy-1-prop-2-enyl-4-pyrimidinone cid_1618319 ZINC59094912 BDBM37787 MLS000114539 1-allyl-2-(butylthio)-6-hydroxy-pyrimidin-4-one CHEMBL1334790 2-butylsulfanyl-6-hydroxy-1-prop-2-enylpyrimidin-4-one AC1LUV3U HMS2252F14 ZINC8584059 CCG-115384 MolPort-002-212-513 2-(butylsulfanyl)-6-hydroxy-3-(prop-2-en-1-yl)pyrimidin-4(3H)-one [ Show all ]
Inchi Key	BXPFOURZBFIMBA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H16N2O2S/c1-3-5-7-16-11-12-9(14)8-10(15)13(11)6-4-2/h4,8,14H,2-3,5-7H2,1H3
PubChem CID	135406754
ChEMBL	CHEMBL1334790
IUPHAR	N/A
BindingDB	37787
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	30300.0 nM	N/A	BindingDB
Ki	19800.0 nM	N/A	BindingDB
Ki	30300.0 nM	PubChem BioAssay data set	ChEMBL

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