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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	fMet-Leu-Phe receptor
Species	Homo sapiens (Human)
Gene	FPR1
Synonym	NFPR N-formylpeptide chemoattractant receptor N-formyl peptide receptor FPR1 FPR formyl peptide receptor 1 fMLP receptor fMLF-R [ Show all ]
Disease	Inflammatory disease Peptic ulcer
Length	350
Amino acid sequence	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
UniProt	P21462
Protein Data Bank	N/A
GPCR-HGmod model	P21462
3D structure model	This predicted structure model is from GPCR-EXP P21462.
BioLiP	N/A
Therapeutic Target Database	T87831
ChEMBL	CHEMBL3359
IUPHAR	222
DrugBank	BE0000995

Ligand

Name	AC1MN97W
Molecular formula	C24H20N4O4
IUPAC name	3-(1-benzofuran-2-carbonyl)-4-hydroxy-1-(3-imidazol-1-ylpropyl)-2-pyridin-3-yl-2H-pyrrol-5-one
Molecular weight	428.448
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.7
Synonyms	MolPort-000-230-191 CCG-116728 4-(1-benzofuran-2-ylcarbonyl)-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-5-(pyridin-3-yl)-1,5-dihydro-2H-pyrrol-2-one HMS3430O17 AKOS001685626 STK515958 4-(1-benzofuran-2-ylcarbonyl)-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-5-pyridin-3-yl-1,5-dihydro-2H-pyrrol-2-one MCULE-7576450592 AKOS016080495 CHEMBL1479223 [ Show all ]
Inchi Key	CEQNTDUYECRXCN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H20N4O4/c29-22(19-13-16-5-1-2-7-18(16)32-19)20-21(17-6-3-8-25-14-17)28(24(31)23(20)30)11-4-10-27-12-9-26-15-27/h1-3,5-9,12-15,21,30H,4,10-11H2
PubChem CID	3274349
ChEMBL	CHEMBL1479223
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
KI_MICROM	<44.3 um	PubChem BioAssay data set	ChEMBL

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