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Check the ligand table for details.
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Ligand

Name	raloxifene
Molecular formula	C28H27NO4S
IUPAC name	[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone
Molecular weight	473.587
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	6.1
Synonyms	LY-156758 NCGC00015889-02 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]-thiophene NCGC00092353-04 82640-04-8 (hydrochloride) Prestwick2_000862 API0003075 Raloxifeno [Spanish] BSPBio_000903 SPBio_002824 CCRIS 7129 [6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone DB00481 (6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone GZUITABIAKMVPG-UHFFFAOYSA-N 15189-EP2295426A1 KBioGR_002361 15189-EP2311825A1 [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone 15189-EP2311840A1 Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)- NCGC00015889-06 6-hydroxy-2-(4-hydroxyphenyl)-3[-4-(2-piperidinoethoxy)benzoyl]benzo [b]thiophene NSC747974 AC-8399 Raloxifene (extended-release, CDT) BDBM19441 Raxeto (TN) C28H27NO4S VU0155042-3 CHEMBL81 DSSTox_RID_77076 15189-EP2280012A2 KB-145991 15189-EP2301933A1 Lopac-R-1402 [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone LY 139481 15189-EP2316832A1 MRF-0000684 6-hydroxy-2-(4-hydoxyphenyl)-3[-4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene NCGC00015889-10 6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl 4-[2-(1-piperidinyl)ethoxy]phenyl methanone Prestwick0_000862 AKOS015896267 Raloxifene, 6 BPBio1_000995 SCHEMBL6144 CC-34210 [2-(4-Hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][4-(2-(1-piperidinyl)ethoxy)phenyl]methanone D01XBA FT-0630926 15189-EP2292615A1 KBio2_007497 15189-EP2308855A1 [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone LY139481 2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol NCGC00015889-04 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene NCGC00260151-01 84449-90-1 Prestwick3_000862 AS-35086 Raloxifenum C-22734 Tox21_202603 CHEBI:8772 [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone DSSTox_CID_3550 15189-EP2270008A1 HMS2089F06 15189-EP2295427A1 KBioSS_002364 15189-EP2311827A1 15189-EP2311842A2 Methanone, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]- 449R901 NCGC00015889-07 6-hydroxy-2-(4-hydroxyphenyl)-3[-4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene Optruma AC1L1JGT Raloxifene (INN) BIDD:ER0216 SBI-0051021.P002 CAS-82640-04-8 YX9162EO3I cid_11071264 DTXSID3023550 15189-EP2281815A1 KBio2_002361 15189-EP2305640A2 Lopac0_001051 [6-hydroxy-2-(4-hydroxyphenyl)benzo-[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone LY-139481 15189-EP2316833A1 NCGC00015889-01 6-Hydroxy-2-(4-Hydroxyphenyl)-3-[4(2-Piperidinoethoxy)benzoyl]benzo[b]thiophene NCGC00092353-02 6-hydroxy-2-(4-hyroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene Prestwick1_000862 AN-8070 Raloxifeno BRD-K63828191-003-11-5 SMP2_000095 CCG-205128 [2-(4-hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone D08465 (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone GTPL2820 15189-EP2292617A1 KBio3_002840 15189-EP2311808A1 [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1piperidinyl)ethoxy]phenyl]methanone MCULE-4598311006 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol NCGC00015889-05 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2piperidinoethoxy)-benzoyl]benzo[b]thiophene NSC-747974 AB0073011 BCP09772 Raloxifenum [Latin] C07228 UNII-YX9162EO3I DSSTox_GSID_23550 15189-EP2272825A2 HSDB 7460 15189-EP2301928A1 Keoxifene 15189-EP2311829A1 [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl]{4-[(2-piperidin-1-ylethyl)oxy]phenyl}methanone 15189-EP2314581A1 Methanone,[6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]- 6-hydroxy-2-(4-hydoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene NCGC00015889-08 6-hydroxy-2-(4-hydroxyphenyl)-3[-4-(2piperidinoethoxy)benzoyl]benzo[b]thiophene Pharoxifene AJ-23384 Raloxifene [INN:BAN] BIDD:GT0795 SC-17311 CAS-84449-90-1 ZINC538275 cMAP_000032 Eviden (TN) 15189-EP2289892A1 KBio2_004929 15189-EP2305671A1 LS-177821 [6-hydroxy-2-(4-hydroxyphenyl)benzothiophen-3-yl]-[4-[2-(1-piperidyl)ethoxy]phenyl]methanone [ Show all ]
Inchi Key	GZUITABIAKMVPG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2
PubChem CID	5035
ChEMBL	CHEMBL81
IUPHAR	2820
BindingDB	19441
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
109454	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
109455	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
109474	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
109458	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
109465	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
109469	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
446012	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
109468	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
109461	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
109457	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
109459	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
109464	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
109467	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
109456	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
109470	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
109462	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
553795	G-protein coupled estrogen receptor 1	Q99527	GPER1	Homo sapiens (Human)	375
109471	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
109460	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
109466	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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