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| Name | Melanin-concentrating hormone receptor 1 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Mchr1 |
| Synonym | SLC-1 MCHR-1 MCHR MCH1R MCH1 receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 353 |
| Amino acid sequence | MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT |
| UniProt | P97639 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL1075228 |
| IUPHAR | 280 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 413 |  CHEMBL217751 | C19H16F3N3O | 359.352 | 6 / 2 | 3.8 | Yes |
| 989 |  CHEMBL1830045 | C25H25N3O2 | 399.494 | 3 / 0 | 3.1 | Yes |
| 463130 |  CHEMBL3601377 | C23H26N4O4 | 422.485 | 7 / 0 | 1.7 | Yes |
| 3661 |  CHEMBL216192 | C28H32N4O3 | 472.589 | 4 / 3 | 4.5 | Yes |
| 521547 |  CHEMBL3793395 | C25H24FN3O2 | 417.484 | 4 / 0 | 4.4 | Yes |
| 4102 |  CHEMBL394793 | C28H38FN3O2 | 467.629 | 4 / 2 | 5.0 | Yes |
| 4104 |  CHEMBL244369 | C28H38FN3O2 | 467.629 | 4 / 2 | 5.0 | Yes |
| 5553 |  CHEMBL1914639 | C28H36ClN3O2 | 482.065 | 3 / 1 | 4.8 | Yes |
| 521704 |  CHEMBL3771000 | C22H21N3O2 | 359.429 | 3 / 0 | 4.2 | Yes |
| 8962 |  CHEMBL208720 | C23H23N5O2S | 433.53 | 7 / 1 | 3.2 | Yes |
| 9717 |  CHEMBL1818811 | C29H30N2O2 | 438.571 | 3 / 1 | 5.3 | No |
| 11287 |  CHEMBL217502 | C26H27F3N4O | 468.524 | 7 / 2 | 4.5 | Yes |
| 11868 |  CHEMBL2059417 | C27H31N3O2 | 429.564 | 4 / 1 | 4.9 | Yes |
| 13939 |  CHEMBL224943 | C29H29ClN2O | 457.014 | 3 / 1 | 6.3 | No |
| 522004 |  CHEMBL3769550 | C22H19ClN4O2 | 406.87 | 3 / 0 | 4.4 | Yes |
| 27312 |  CHEMBL1818793 | C25H28N2O2S | 420.571 | 4 / 1 | 5.0 | Yes |
| 522388 |  CHEMBL3769682 | C22H20N4O2 | 372.428 | 4 / 0 | 2.9 | Yes |
| 27822 |  CHEMBL244370 | C31H42FN3O2 | 507.694 | 4 / 2 | 5.9 | No |
| 28344 |  CHEMBL389128 | C28H32N2O2 | 428.576 | 3 / 1 | 5.7 | No |
| 31740 |  CHEMBL384848 | C23H24F3N3O | 415.46 | 6 / 1 | 5.5 | No |
| 31917 |  CHEMBL2029372 | C28H26FN3O | 439.534 | 4 / 1 | 5.4 | No |
| 33599 |  CHEMBL2059415 | C26H28FN3O2 | 433.527 | 5 / 1 | 3.8 | Yes |
| 34962 |  CHEMBL1818783 | C26H27ClN2O | 418.965 | 2 / 1 | 6.0 | No |
| 35184 |  CHEMBL1830044 | C23H20ClN3O | 389.883 | 2 / 1 | 3.7 | Yes |
| 522597 |  CHEMBL3769816 | C24H20FN3O3 | 417.44 | 5 / 0 | 3.9 | Yes |
| 36072 |  CHEMBL216576 | C29H26F3N3O | 489.542 | 6 / 1 | 6.5 | No |
| 39412 |  CHEMBL373887 | C34H36N4O4 | 564.686 | 5 / 3 | 6.1 | No |
| 44131 |  CHEMBL424720 | C30H35N3O3 | 485.628 | 4 / 2 | 5.0 | Yes |
| 522829 |  CHEMBL3771307 | C23H20BrN3O2 | 450.336 | 3 / 0 | 4.6 | Yes |
| 46353 |  CHEMBL215662 | C24H24F3N3O | 427.471 | 6 / 1 | 5.4 | No |
| 47836 |  CHEMBL1914638 | C27H33ClN2O3 | 469.022 | 4 / 0 | 5.0 | Yes |
| 469036 |  CHEMBL3618337 | C23H21ClN4O3 | 436.896 | 5 / 1 | 3.8 | Yes |
| 51475 |  CHEMBL243794 | C23H27ClN2O2 | 398.931 | 3 / 1 | 4.0 | Yes |
| 523077 |  CHEMBL3769928 | C22H20N4O2 | 372.428 | 4 / 0 | 2.9 | Yes |
| 55379 |  CHEMBL210191 | C24H22ClN5O | 431.924 | 5 / 1 | 3.9 | Yes |
| 55380 |  CHEMBL211223 | C24H22ClN5O | 431.924 | 5 / 1 | 3.9 | Yes |
| 55416 |  CHEMBL211340 | C24H25N5OS | 431.558 | 6 / 1 | 4.1 | Yes |
| 56731 |  CHEMBL384362 | C24H22F3N3O2 | 441.454 | 7 / 1 | 4.5 | Yes |
| 58973 |  CHEMBL2059419 | C27H31N3O2 | 429.564 | 4 / 1 | 4.8 | Yes |
| 58975 |  compound (R)-10a | C27H31N3O2 | 429.564 | 4 / 1 | 4.8 | Yes |
| 58977 |  CHEMBL2059418 | C27H31N3O2 | 429.564 | 4 / 1 | 4.8 | Yes |
| 59046 |  CHEMBL390377 | C20H20Cl2N2O3 | 407.291 | 4 / 1 | 3.9 | Yes |
| 523283 |  CHEMBL3769548 | C19H16F3NO4 | 379.335 | 7 / 1 | 5.1 | No |
| 59962 |  CHEMBL263686 | C36H47F3N3O+ | 594.787 | 5 / 1 | 10.5 | No |
| 523318 |  CHEMBL3771335 | C18H16F3N3O3 | 379.339 | 7 / 1 | 4.6 | Yes |
| 63484 |  CHEMBL216010 | C27H29FN4O3 | 476.552 | 5 / 3 | 4.3 | Yes |
| 67657 |  CHEMBL2147477 | C25H35FN6S | 470.655 | 4 / 3 | 2.9 | Yes |
| 70799 |  CHEMBL215279 | C29H33N3O3 | 471.601 | 4 / 2 | 4.8 | Yes |
| 471735 |  CHEMBL3618328 | C23H21ClN4O4 | 452.895 | 6 / 1 | 3.9 | Yes |
| 523696 |  CHEMBL3578244 | C22H18F3N3O2S | 445.46 | 7 / 0 | 4.2 | Yes |
| 523727 |  CHEMBL3770706 | C24H18ClN3O2 | 415.877 | 3 / 0 | 5.3 | No |
| 75523 |  CHEMBL1818802 | C29H30ClN3O | 472.029 | 3 / 1 | 5.3 | No |
| 76133 |  CHEMBL243128 | C32H37Cl2N3O2 | 566.567 | 3 / 2 | 6.9 | No |
| 77072 |  CHEMBL2059414 | C27H32N4O2 | 444.579 | 4 / 2 | 4.3 | Yes |
| 79487 |  CHEMBL1914632 | C29H37ClN2O2 | 481.077 | 3 / 0 | 5.4 | No |
| 523857 |  CHEMBL3770135 | C22H19ClN4O2 | 406.87 | 4 / 0 | 4.1 | Yes |
| 523860 |  CHEMBL3793182 | C23H22FN3O2 | 391.446 | 4 / 0 | 3.9 | Yes |
| 84216 |  CHEMBL585664 | C27H28F2N4O3 | 494.543 | 8 / 0 | 2.3 | Yes |
| 473470 |  CHEMBL3588863 | C24H25ClN4O5 | 484.937 | 7 / 1 | 3.0 | Yes |
| 524012 |  CHEMBL3793700 | C24H22FN3O2 | 403.457 | 4 / 0 | 3.9 | Yes |
| 89019 |  Snap7941 | C31H37F2N5O6 | 613.663 | 9 / 3 | 2.7 | No |
| 524108 |  CHEMBL3794150 | C22H18F3N3O2S | 445.46 | 7 / 0 | 3.8 | Yes |
| 524175 |  CHEMBL3769758 | C22H17FN4O2 | 388.402 | 5 / 0 | 3.2 | Yes |
| 92719 |  CHEMBL214177 | C24H31N3O3 | 409.53 | 4 / 2 | 3.6 | Yes |
| 524188 |  CHEMBL3769964 | C23H18F3N3O3 | 441.41 | 7 / 0 | 5.2 | No |
| 474396 |  CHEMBL3616496 | C22H22ClN5O6S | 519.957 | 9 / 1 | 1.6 | No |
| 93296 |  CHEMBL2059423 | C28H34N4O2 | 458.606 | 5 / 1 | 4.2 | Yes |
| 474445 |  CHEMBL3618336 | C23H22ClN3O4 | 439.896 | 5 / 1 | 4.1 | Yes |
| 94076 |  CHEMBL242901 | C34H43N3O2 | 525.737 | 3 / 2 | 6.4 | No |
| 524227 |  CHEMBL3769899 | C26H27N3O2 | 413.521 | 3 / 0 | 5.1 | No |
| 474615 |  CHEMBL3618335 | C22H20ClN5O2 | 421.885 | 5 / 1 | 3.5 | Yes |
| 474716 |  CHEMBL3618324 | C25H25ClN4O3 | 464.95 | 5 / 0 | 4.7 | Yes |
| 95945 |  CHEMBL215841 | C23H29N3O3 | 395.503 | 4 / 2 | 3.2 | Yes |
| 96007 |  CHEMBL379933 | C22H20FN5OS | 421.494 | 7 / 1 | 3.4 | Yes |
| 96010 |  CHEMBL378869 | C22H20FN5OS | 421.494 | 7 / 1 | 3.4 | Yes |
| 99303 |  CHEMBL1818786 | C29H34N2O | 426.604 | 2 / 1 | 6.7 | No |
| 524448 |  CHEMBL3793953 | C23H21N3O2 | 371.44 | 3 / 0 | 3.2 | Yes |
| 100142 |  CHEMBL388234 | C33H41N3O2 | 511.71 | 3 / 2 | 6.0 | No |
| 100746 |  CHEMBL2059410 | C27H31N3O2 | 429.564 | 4 / 1 | 5.2 | No |
| 475692 |  CHEMBL3589154 | C23H21ClN2O4S | 456.941 | 6 / 1 | 4.6 | Yes |
| 107419 |  T-226296 | C26H27FN2O | 402.513 | 3 / 1 | 5.4 | No |
| 109742 |  CHEMBL215316 | C25H25F3N4O2 | 470.496 | 7 / 2 | 4.1 | Yes |
| 524753 |  CHEMBL3793001 | C20H16F3N3O2S | 419.422 | 7 / 0 | 3.8 | Yes |
| 111650 |  CHEMBL208551 | C26H27N5O2 | 441.535 | 6 / 1 | 3.6 | Yes |
| 476801 |  CHEMBL3618323 | C19H15ClN4O3 | 382.804 | 5 / 0 | 3.5 | Yes |
| 524796 |  CHEMBL3792529 | C23H20ClN3O2 | 405.882 | 3 / 0 | 3.9 | Yes |
| 113738 |  CHEMBL224438 | C23H30N2O | 350.506 | 2 / 1 | 4.3 | Yes |
| 113740 |  CHEMBL2096865 | C23H30N2O | 350.506 | 2 / 1 | 4.3 | Yes |
| 524810 |  CHEMBL3793625 | C24H22ClN3O2 | 419.909 | 3 / 0 | 4.2 | Yes |
| 524846 |  CHEMBL3770850 | C23H21FN4O3 | 420.444 | 5 / 0 | 3.3 | Yes |
| 116003 |  CHEMBL224519 | C19H20Cl2N2O | 363.282 | 2 / 1 | 4.1 | Yes |
| 477265 |  CHEMBL3618327 | C24H22ClN3O4 | 451.907 | 5 / 1 | 4.3 | Yes |
| 117230 |  CHEMBL244003 | C29H32N2O3 | 456.586 | 4 / 1 | 4.9 | Yes |
| 119010 |  CHEMBL387725 | C19H22N2O | 294.398 | 2 / 1 | 2.9 | Yes |
| 524991 |  CHEMBL3770776 | C23H18F3N3O3 | 441.41 | 7 / 0 | 5.7 | No |
| 122539 |  CHEMBL2059513 | C27H32N4O3 | 460.578 | 5 / 3 | 3.2 | Yes |
| 122540 |  CHEMBL2059512 | C27H32N4O3 | 460.578 | 5 / 3 | 3.2 | Yes |
| 122542 |  CHEMBL2059511 | C27H32N4O3 | 460.578 | 5 / 3 | 3.2 | Yes |
| 123108 |  CHEMBL1830047 | C25H24FN3O2 | 417.484 | 4 / 1 | 3.5 | Yes |
| 125266 |  CHEMBL225073 | C24H35ClN2O | 403.007 | 3 / 1 | 6.3 | No |
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