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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL215316
Molecular formula	C25H25F3N4O2
IUPAC name	N-[2-(3-acetamidopyrrolidin-1-yl)quinolin-6-yl]-3-[4-(trifluoromethyl)phenyl]propanamide
Molecular weight	470.496
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.1
Synonyms	SCHEMBL5873543 BDBM50193687 N-(2-(3-acetamidopyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide
Inchi Key	HAEBQPAGVYKXCG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25F3N4O2/c1-16(33)29-21-12-13-32(15-21)23-10-5-18-14-20(8-9-22(18)31-23)30-24(34)11-4-17-2-6-19(7-3-17)25(26,27)28/h2-3,5-10,14,21H,4,11-13,15H2,1H3,(H,29,33)(H,30,34)
PubChem CID	22018914
ChEMBL	CHEMBL215316
IUPHAR	N/A
BindingDB	50193687
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
109741	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
109742	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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