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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL217502
Molecular formula	C26H27F3N4O
IUPAC name	N-[2-(2,7-diazaspiro[4.4]nonan-2-yl)quinolin-6-yl]-3-[4-(trifluoromethyl)phenyl]propanamide
Molecular weight	468.524
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.5
Synonyms	SCHEMBL5873586 BDBM50193700 N-(2-(2,7-diazaspiro[4.4]nonan-2-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide
Inchi Key	APRWXACNSKEQER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27F3N4O/c27-26(28,29)20-5-1-18(2-6-20)3-10-24(34)31-21-7-8-22-19(15-21)4-9-23(32-22)33-14-12-25(17-33)11-13-30-16-25/h1-2,4-9,15,30H,3,10-14,16-17H2,(H,31,34)
PubChem CID	22018957
ChEMBL	CHEMBL217502
IUPHAR	N/A
BindingDB	50193700
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11286	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
11287	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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