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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	compound (R)-10a
Molecular formula	C27H31N3O2
IUPAC name	4-(cyclopropylmethoxy)-N-[8-methyl-3-[(1R)-1-pyrrolidin-1-ylethyl]quinolin-7-yl]benzamide
Molecular weight	429.564
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	CHEMBL2059420 GTPL8587 4-(cyclopropylmethoxy)-N-[8-methyl-3-[(1R)-1-pyrrolidin-1-ylethyl]quinolin-7-yl]benzamide BDBM50388452 MQ-1 D0P5QW [ Show all ]
Inchi Key	DFWKNBVJNXPUBW-LJQANCHMSA-N
Inchi ID	InChI=1S/C27H31N3O2/c1-18-25(29-27(31)21-7-10-24(11-8-21)32-17-20-5-6-20)12-9-22-15-23(16-28-26(18)22)19(2)30-13-3-4-14-30/h7-12,15-16,19-20H,3-6,13-14,17H2,1-2H3,(H,29,31)/t19-/m1/s1
PubChem CID	57521365
ChEMBL	CHEMBL2059420
IUPHAR	8587
BindingDB	50388452
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58974	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
58975	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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