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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melanin-concentrating hormone receptor 1
Species	Rattus norvegicus (Rat)
Gene	Mchr1
Synonym	SLC-1 MCHR-1 MCHR MCH1R MCH1 receptor MCH-R1 MCH-1R MCH receptor 1 GPR24 G-protein coupled receptor 24 G protein-coupled receptor 24 somatostatin receptor-like protein [ Show all ]
Disease	N/A for non-human GPCRs
Length	353
Amino acid sequence	MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT
UniProt	P97639
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075228
IUPHAR	280
DrugBank	N/A

Ligand

Name	CHEMBL224438
Molecular formula	C23H30N2O
IUPAC name	4-phenyl-N-[[(2R)-1-(2-phenylethyl)pyrrolidin-2-yl]methyl]butanamide
Molecular weight	350.506
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.3
Synonyms	828928-57-0 Benzenebutanamide, N-[[(2R)-1-(2-phenylethyl)-2-pyrrolidinyl]methyl]- (R)-N-(1-phenethylpyrrolidin-2-ylmethyl)-4-phenylbutyramide CTK3D5486 AKOS030583670 (S)-N-(1-phenethylpyrrolidin-2-ylmethyl)-4-phenylbutyramide DTXSID50464254 BDBM50158496 [ Show all ]
Inchi Key	HFTIKXYSNDRVRI-JOCHJYFZSA-N
Inchi ID	InChI=1S/C23H30N2O/c26-23(15-7-13-20-9-3-1-4-10-20)24-19-22-14-8-17-25(22)18-16-21-11-5-2-6-12-21/h1-6,9-12,22H,7-8,13-19H2,(H,24,26)/t22-/m1/s1
PubChem CID	11385742
ChEMBL	CHEMBL224438
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3100.0 nM	PMID15615535	ChEMBL

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