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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3601377
Molecular formula	C23H26N4O4
IUPAC name	2-[2-[4-[(dimethylamino)methyl]-2-methylphenyl]-2-oxoethyl]-5-[(5-methoxypyridin-2-yl)methoxy]pyridazin-3-one
Molecular weight	422.485
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	1.7
Synonyms	ACBKFGPDANWBLT-UHFFFAOYSA-N US8933079, 150 2-(2-(4-((dimethylamino)methyl)-2-methylphenyl)-2-oxoethyl)-5-((5-methoxypyridin-2-yl)methoxy)pyridazin-3(2H)-one SCHEMBL15238663 BDBM142122 US8933079, 9.1 2-[2-(4-Dimethylaminomethyl-2-methyl-phenyl)-2-oxo-ethyl]-5-(5-methoxy-pyridin-2-ylmethoxy)-2H-pyridazin-3-one US8933079, 149 BI-186908 1453500-36-1 SB19163 [ Show all ]
Inchi Key	ACBKFGPDANWBLT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26N4O4/c1-16-9-17(13-26(2)3)5-8-21(16)22(28)14-27-23(29)10-20(12-25-27)31-15-18-6-7-19(30-4)11-24-18/h5-12H,13-15H2,1-4H3
PubChem CID	71714121
ChEMBL	CHEMBL3601377
IUPHAR	N/A
BindingDB	142122
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463131	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
1403	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
463130	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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