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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL217751
Molecular formula	C19H16F3N3O
IUPAC name	N-(2-aminoquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]propanamide
Molecular weight	359.352
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.8
Synonyms	N-(2-aminoquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide ZINC36351894 BDBM50193697
Inchi Key	AAOYBQGKRBCNLH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16F3N3O/c20-19(21,22)14-5-1-12(2-6-14)3-10-18(26)24-15-7-8-16-13(11-15)4-9-17(23)25-16/h1-2,4-9,11H,3,10H2,(H2,23,25)(H,24,26)
PubChem CID	44417982
ChEMBL	CHEMBL217751
IUPHAR	N/A
BindingDB	50193697
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
412	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
413	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353
414	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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