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Ligand

NameCHEMBL3618337
Molecular formulaC23H21ClN4O3
IUPAC name6-(4-chlorophenyl)-3-[4-[(3R)-3-hydroxypyrrolidin-1-yl]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Molecular weight436.896
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP3.8
SynonymsBDBM50120674
SCHEMBL13418849
Inchi KeyCSUYOWVTAHGJSU-LJQANCHMSA-N
Inchi IDInChI=1S/C23H21ClN4O3/c1-31-22-11-18(6-7-20(22)26-9-8-19(29)13-26)27-14-25-28-12-16(10-21(28)23(27)30)15-2-4-17(24)5-3-15/h2-7,10-12,14,19,29H,8-9,13H2,1H3/t19-/m1/s1
PubChem CID45279583
ChEMBLCHEMBL3618337
IUPHARN/A
BindingDB50120674
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
469036Melanin-concentrating hormone receptor 1P97639Mchr1Rattus norvegicus (Rat)353
469037Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422

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