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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3794150
Molecular formula	C22H18F3N3O2S
IUPAC name	1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-[[5-(trifluoromethyl)thiophen-3-yl]methoxy]pyridin-2-one
Molecular weight	445.46
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50163470 FXCYREGHIBLSLY-UHFFFAOYSA-N 1-(2-Cyclopropyl-1-methyl-1H-benzimidazol-6-yl)-4-((5-(trifluoromethyl)-3-thienyl)methoxy)pyridin-2(1H)-one SCHEMBL15112009
Inchi Key	FXCYREGHIBLSLY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H18F3N3O2S/c1-27-18-9-15(4-5-17(18)26-21(27)14-2-3-14)28-7-6-16(10-20(28)29)30-11-13-8-19(31-12-13)22(23,24)25/h4-10,12,14H,2-3,11H2,1H3
PubChem CID	89691065
ChEMBL	CHEMBL3794150
IUPHAR	N/A
BindingDB	50163470
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
524107	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
524108	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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