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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL373887
Molecular formula	C34H36N4O4
IUPAC name	4-(3,4-dimethylphenoxy)-3-[(4-phenoxyphenyl)carbamoylamino]-N-(2-pyrrolidin-1-ylethyl)benzamide
Molecular weight	564.686
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	6.1
Synonyms	SCHEMBL6368857 1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(4-phenoxyphenyl)urea BDBM50192533
Inchi Key	CDLVRUWCUTVUDT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H36N4O4/c1-24-10-14-30(22-25(24)2)42-32-17-11-26(33(39)35-18-21-38-19-6-7-20-38)23-31(32)37-34(40)36-27-12-15-29(16-13-27)41-28-8-4-3-5-9-28/h3-5,8-17,22-23H,6-7,18-21H2,1-2H3,(H,35,39)(H2,36,37,40)
PubChem CID	11563153
ChEMBL	CHEMBL373887
IUPHAR	N/A
BindingDB	50192533
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39410	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
39411	Melanin-concentrating hormone receptor 1	Q8JZL2	Mchr1	Mus musculus (Mouse)	353
39412	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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