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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	T-226296
Molecular formula	C26H27FN2O
IUPAC name	N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)benzamide
Molecular weight	402.513
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.4
Synonyms	4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide D0TV4N N-[6-(dimethylaminomethyl)-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)benzamide KB-80782 S-20951 102690-EP2272841A1 CHEMBL178707 N-(6-((dimethylamino)methyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-4''-fluorobiphenyl-4-carboxamide 331758-35-1 4'-Fluoro-N-[6-[(N,N-dimethylamino)methyl]-5,6,7,8-tetrahydro-2-naphthalenyl)[1,1'-biphenyl]-4-carboxamide GTPL1314 PDSP1_000981 BDBM50150715 LS-193063 SCHEMBL5582818 102690-EP2301936A1 D0L1IZ N-(6-((dimethylamino)methyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-4'-fluoro-[1,1'-biphenyl]-4-carboxamide T226296 4''''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide 4'-Fluoro-N-[6-[(N,N-dimethylamino)methyl]-5,6,7,8-tetrahydro-2-naphthalenyl][1,1'-biphenyl]-4-carboxamide GXAQELJVODWLDD-UHFFFAOYSA-N PDSP2_000965 LS-44229 T 226296 [ Show all ]
Inchi Key	GXAQELJVODWLDD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27FN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30)
PubChem CID	9865843
ChEMBL	CHEMBL178707
IUPHAR	1314
BindingDB	50150715
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
107418	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
107419	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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