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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3769964
Molecular formula	C23H18F3N3O3
IUPAC name	1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[4-(trifluoromethoxy)phenoxy]pyridin-2-one
Molecular weight	441.41
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50149452
Inchi Key	GCJDMMOKYRCMEN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H18F3N3O3/c1-14-22(15-2-3-15)27-20-9-4-16(13-29(14)20)28-11-10-19(12-21(28)30)31-17-5-7-18(8-6-17)32-23(24,25)26/h4-13,15H,2-3H2,1H3
PubChem CID	127029631
ChEMBL	CHEMBL3769964
IUPHAR	N/A
BindingDB	50149452
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
524187	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
524188	Melanin-concentrating hormone receptor 1	P97639	Mchr1	Rattus norvegicus (Rat)	353

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