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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-271046
Molecular formula	C20H22ClN3O3S2
IUPAC name	5-chloro-N-(4-methoxy-3-piperazin-1-ylphenyl)-3-methyl-1-benzothiophene-2-sulfonamide
Molecular weight	451.984
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.2
Synonyms	HMS3651D19 s2856 SCHEMBL194700 5-chloro-N-(4-methoxy-3-piperazin-1-ylphenyl)-3-methyl-1-benzothiophene-2-sulfonamide BCP03713 L3SK5KX24S SB-271,046 Z-3245 2704AH 5-chloro-N~2~-(4-methoxy-3-piperazinophenyl)-3-methyl-1-benzothiophene-2-sulfonamide EX-A2155 PDSP1_001373 SB271046 5-Chloro-N-(4-methoxy-3-(1-piperazinyl)phenyl)-3-methylbenzo(b)thiophene-2-sulfonamide API0006978 KB-60401 Sb 271046 SW219941-1 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide BDBM28583 MolPort-021-806-425 ZINC1489208 AC1NSM3X CHEMBL431298 GTPL276 PDSP2_001357 SB271046 HCl 5-chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide BC282896 L000544 SB 271046 HCl UNII-L3SK5KX24S 209481-20-9 5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride C20H22ClN3O3S2 D07LRJ NCGC00386219-06 SB19511 AKOS005266659 [ Show all ]
Inchi Key	LOCQRDBFWSXQQI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22ClN3O3S2/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24/h3-6,11-12,22-23H,7-10H2,1-2H3
PubChem CID	5312149
ChEMBL	CHEMBL431298
IUPHAR	276
BindingDB	28583
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
192215	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
192223	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
192219	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
192226	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
192221	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
192210	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
192216	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
192213	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
192224	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
192209	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
192212	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
192214	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
192218	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
192225	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
192220	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
192211	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
192222	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
192217	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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