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Name | Mu-type opioid receptor |
---|---|
Species | Bos taurus (Bovine) |
Gene | OPRM1 |
Synonym | M-OR-1 MOR-1 |
Disease | N/A for non-human GPCRs |
Length | 401 |
Amino acid sequence | MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP |
UniProt | P79350 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3041 |
IUPHAR | N/A |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
4462 | CHEMBL60270 | C17H24N2O | 272.392 | 3 / 2 | 2.7 | Yes |
6812 | CHEMBL41098 | C38H42N4O8S2 | 746.894 | 12 / 4 | 2.1 | No |
7628 | CHEMBL413258 | C31H31N3O6 | 541.604 | 7 / 1 | 4.0 | No |
30360 | morphine | C17H19NO3 | 285.343 | 4 / 2 | 0.8 | Yes |
30368 | Morphinan-3,6.alpha.-diol, 7,8-didehydro-4,5.alpha.-epoxy-17-methyl- | C17H19NO3 | 285.343 | 4 / 2 | 0.8 | Yes |
38080 | CHEMBL3038198 | C27H32N2O3S | 464.624 | 6 / 0 | 5.1 | No |
38081 | CHEMBL2021333 | C27H32N2O3S | 464.624 | 6 / 0 | 5.1 | No |
39730 | CHEMBL107164 | C27H27N3O6 | 489.528 | 7 / 2 | 2.9 | Yes |
50210 | CHEMBL290855 | C15H21NO2 | 247.338 | 3 / 2 | 2.1 | Yes |
50214 | CHEMBL36707 | C15H21NO2 | 247.338 | 3 / 2 | 2.1 | Yes |
51337 | CHEMBL554230 | C22H29ClN2O3 | 404.935 | 4 / 2 | N/A | N/A |
53728 | CHEMBL290701 | C44H50N4O8S2 | 827.024 | 12 / 4 | 3.6 | No |
60001 | CHEMBL2304424 | C46H54N4O8S2 | 855.078 | 12 / 4 | 4.0 | No |
68384 | CHEMBL554230 | C22H28N2O3 | 368.477 | 4 / 1 | 2.9 | Yes |
72174 | CHEMBL299460 | C17H25NO2 | 275.392 | 3 / 2 | 2.6 | Yes |
98923 | CHEMBL3038193 | C31H41NO5Si | 535.756 | 6 / 0 | N/A | No |
103213 | CHEMBL327111 | C31H33N3O6 | 543.62 | 7 / 1 | 4.0 | No |
110495 | CHEMBL57879 | C16H23NO2 | 261.365 | 3 / 3 | 2.7 | Yes |
116075 | N-CPM-CACO | C30H31N3O6 | 529.593 | 7 / 1 | 4.2 | No |
116078 | CHEMBL610885 | C30H31N3O6 | 529.593 | 7 / 1 | 4.2 | No |
119395 | CHEMBL108794 | C27H25N3O6 | 487.512 | 7 / 1 | 3.0 | Yes |
124141 | CHEMBL418460 | C16H21NO | 243.35 | 2 / 1 | 3.0 | Yes |
132261 | BDBM50030144 | C19H22N2O4S | 374.455 | 6 / 3 | 1.1 | Yes |
132265 | TAMO | C19H22N2O4S | 374.455 | 6 / 3 | 1.1 | Yes |
134986 | CHEMBL1281 | C17H21NO3 | 287.359 | 4 / 2 | 1.8 | Yes |
134993 | Hydromorphine | C17H21NO3 | 287.359 | 4 / 2 | 1.8 | Yes |
147018 | CHEMBL287726 | C16H23NO | 245.366 | 2 / 1 | 3.7 | Yes |
155938 | CHEMBL110238 | C26H23N3O6 | 473.485 | 7 / 2 | 2.7 | Yes |
166843 | N-CBM-TAMO | C46H54N4O8S2 | 855.078 | 12 / 4 | 4.7 | No |
169385 | CHEMBL59840 | C16H20N4O2 | 300.362 | 5 / 1 | 2.0 | Yes |
184206 | BDBM85393 | C27H27ClN2O4 | 478.973 | 5 / 1 | 3.9 | Yes |
191182 | CHEMBL431947 | C18H27NO2 | 289.419 | 3 / 1 | 3.1 | Yes |
200317 | BDBM85395 | C30H31ClN2O4 | 519.038 | 5 / 1 | 5.0 | No |
202145 | CHEMBL294616 | C30H39N5O7S2 | 645.79 | 10 / 7 | -0.6 | No |
203490 | CUMI-101 | C19H27N5O3 | 373.457 | 6 / 0 | 1.8 | Yes |
215368 | CHEMBL288178 | C23H25ClN2O4 | 428.913 | 5 / 2 | 3.3 | Yes |
219897 | CHEMBL320060 | C28H29N3O6 | 503.555 | 7 / 1 | 3.2 | No |
220310 | BDBM86519 | C21H25NO5 | 371.433 | 6 / 0 | 2.5 | Yes |
231203 | CHEMBL610531 | C24H27NO5 | 409.482 | 6 / 2 | 0.7 | Yes |
231204 | Naltrexone analogue | C24H27NO5 | 409.482 | 6 / 2 | 0.7 | Yes |
242000 | CHEMBL110666 | C28H27N3O6 | 501.539 | 7 / 1 | 3.2 | No |
242107 | Diprenorphine | C26H35NO4 | 425.569 | 5 / 2 | 3.6 | Yes |
242463 | CHEMBL58059 | C16H24N2O | 260.381 | 3 / 3 | 2.4 | Yes |
242467 | CHEMBL294226 | C16H23NO2 | 261.365 | 3 / 2 | 2.1 | Yes |
247939 | CHEMBL323430 | C27H25N3O6 | 487.512 | 7 / 2 | 2.9 | Yes |
250600 | CHEMBL2021332 | C26H30N2O3S | 450.597 | 6 / 1 | 4.8 | Yes |
250601 | CHEMBL3038194 | C26H30N2O3S | 450.597 | 6 / 1 | 4.8 | Yes |
254399 | CHEMBL3038199 | C28H31NO5 | 461.558 | 6 / 1 | 3.6 | Yes |
255719 | CHEMBL301421 | C17H25NO | 259.393 | 2 / 1 | 3.8 | Yes |
257006 | CHEMBL105827 | C30H33N3O6 | 531.609 | 7 / 2 | 3.4 | No |
263251 | CHEMBL607068 | C26H25N3O6 | 475.501 | 7 / 2 | 2.7 | Yes |
268347 | CHEMBL290616 | C20H21ClN2O4 | 388.848 | 5 / 2 | 2.3 | Yes |
282568 | CHEMBL61644 | C17H25NO2 | 275.392 | 3 / 1 | 2.8 | Yes |
285816 | 6-AcDHM | C19H23NO4 | 329.396 | 5 / 1 | 2.4 | Yes |
297281 | CHEMBL108406 | C30H31N3O6 | 529.593 | 7 / 2 | 3.6 | No |
314682 | CHEMBL297605 | C40H46N4O8S2 | 774.948 | 12 / 4 | 2.5 | No |
319292 | CHEMBL106189 | C30H29N3O6 | 527.577 | 7 / 2 | 3.6 | No |
330794 | CHEMBL409026 | C15H21NO2 | 247.338 | 3 / 3 | 2.2 | Yes |
334336 | CHEMBL289426 | C23H27ClN2O3 | 414.93 | 4 / 2 | 4.0 | Yes |
335356 | CHEMBL107157 | C30H29N3O6 | 527.577 | 7 / 1 | 3.8 | No |
344680 | CHEMBL611136 | C29H29N3O6 | 515.566 | 7 / 2 | 3.8 | No |
349335 | naloxone | C19H21NO4 | 327.38 | 5 / 2 | 2.1 | Yes |
349345 | Naloxone(-) | C19H21NO4 | 327.38 | 5 / 2 | 2.1 | Yes |
354273 | CHEMBL41366 | C20H23ClN2O3 | 374.865 | 4 / 2 | 3.3 | Yes |
355259 | Cleland's reagent | C4H10O2S2 | 154.242 | 4 / 4 | -0.4 | Yes |
361735 | U50488 | C19H26Cl2N2O | 369.33 | 2 / 0 | 4.4 | Yes |
363055 | CACO | C27H27N3O6 | 489.528 | 7 / 1 | 3.1 | Yes |
363057 | CHEMBL106876 | C27H27N3O6 | 489.528 | 7 / 1 | 3.1 | Yes |
368544 | BDBM81934 | C154H248N42O44S | 3423.99 | 52 / 48 | -14.1 | No |
374599 | Naltrindole | C26H26N2O3 | 414.505 | 4 / 3 | 3.3 | Yes |
382277 | CHEMBL3038197 | C23H26N2O3S | 410.532 | 6 / 1 | 4.1 | Yes |
382278 | CHEMBL2021335 | C23H26N2O3S | 410.532 | 6 / 1 | 4.1 | Yes |
392625 | CHEMBL126243 | C32H37N5O5 | 571.678 | 6 / 5 | 2.3 | No |
401514 | ICI 174,864 | C38H53N5O7 | 691.87 | 8 / 6 | 2.8 | No |
402272 | CHEMBL3038195 | C24H28N2O3S | 424.559 | 6 / 0 | 4.4 | Yes |
402273 | CHEMBL3038196 | C24H28N2O3S | 424.559 | 6 / 0 | 4.4 | Yes |
403727 | CHEMBL163704 | C24H29NO5 | 411.498 | 6 / 2 | 1.2 | Yes |
403728 | CHEMBL3084322 | C24H29NO5 | 411.498 | 6 / 2 | 1.2 | Yes |
425990 | CHEMBL350384 | C20H29NO2 | 315.457 | 3 / 2 | 3.9 | Yes |
426788 | CHEMBL329996 | C34H38N6O5 | 610.715 | 6 / 6 | 2.4 | No |
428860 | DADLE | C29H39N5O7 | 569.659 | 8 / 7 | -1.9 | No |
428867 | 64963-01-5 | C29H39N5O7 | 569.659 | 8 / 7 | -1.9 | No |
428870 | Enkephalin-leu,ala(2) | C29H39N5O7 | 569.659 | 8 / 7 | -1.9 | No |
429957 | CHEMBL317035 | C29H27N3O6 | 513.55 | 7 / 2 | 3.5 | No |
431439 | CHEMBL166355 | C25H31NO6 | 441.524 | 7 / 2 | 0.5 | Yes |
431443 | CHEMBL76023 | C25H31NO6 | 441.524 | 7 / 2 | 0.5 | Yes |
435004 | CHEMBL285250 | C15H21NO | 231.339 | 2 / 1 | 3.2 | Yes |
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